L0881
Lectin from Arachis hypogaea (peanut)
lyophilized powder, Affinity-purified
Sinónimos:
PNA, Peanut agglutinin
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About This Item
Código UNSPSC:
12352202
NACRES:
NA.32
Productos recomendados
Formulario
lyophilized powder
Nivel de calidad
potencia
<0.1 μg per mL agglutination activity
calidad
Affinity-purified
impurezas
salt, free
temp. de almacenamiento
−20°C
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Descripción general
Lectin from Arachis hypogaea (peanut) is a homotetrameric protein of 110 kDa.
Aplicación
Lectin from Arachis hypogaea (peanut) has been used:
- to detect Thomson-Friedenreich antigen
- as a component in PBS to study its effects on cell viability
- to study its ability to block the binding site
Acciones bioquímicas o fisiológicas
Lectin from Arachis hypogaea (peanut) possess specificity towards β -D-Gal(1-3)-D-galNAc residue of Thomson − Friedenreich antigen. It is the most widely used diagnostic and prognostic marker for many squamous cell carcinomas.
PNA does not agglutinate normal human erythrocytes, but strongly agglutinates neuraminidase treated erythrocytes. PNA has potent anti-T activity similar to the anti-T antibody in human sera. The lectin can be used to distinguish between human lymphocyte subsets.
Nota de análisis
Agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, of a 1 mg/ml solution. This activity is the lowest concentration to agglutinate a 2% suspension of neuraminidase treated human blood group O erythrocytes after 1 hr incubation at 25 °C.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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