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H9268

Sigma-Aldrich

Hexadimethrine bromide

≥94% (titration)

Sinónimos:

1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide, Polybrene

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About This Item

Número de CAS:
28728-55-4
Número MDL:
MFCD00133397
Código UNSPSC:
41106502
NACRES:
NA.26

Nivel de calidad

200

Ensayo

≥94% (titration)

temp. de almacenamiento

2-8°C

cadena SMILES

BrCCCBr.N(CCCCCCN(C)C)(C)C

InChI

1S/C10H24N2.C3H6Br2/c1-11(2)9-7-5-6-8-10-12(3)4;4-2-1-3-5/h5-10H2,1-4H3;1-3H2

Clave InChI

KZKAYEGOIJEWQB-UHFFFAOYSA-N

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Descripción general

Hexadimethrine bromide is a quaternary ammonium compound which works as a heparin antagonist. It is also involved in the transformation of low molecular weight DNA.

Aplicación

Hexadimethrine bromide can be used to transfect mammalian cells with DNA. It can be used to increase the efficiency of lipofection transfections.
Hexadimethrine bromide has been used for lentivirus infection in cells. It has been used for infection of cells with retroviral supernatant.

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Referencia del producto
Descripción
Precios

08168

Timestrip Plus™ 8 °C

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H302

Clasificaciones de peligro

Acute Tox. 4 Oral

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
MKCP5260
MKCP0527
MKCM1623
MKCG8652
MKCL4093

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Redei GP
Encyclopedia of Genetics, Genomics, Proteomics, and Informatics (2008)
S Kawai et al.
Molecular and cellular biology, 4(6), 1172-1174 (1984-06-01)
A new procedure for DNA transfection has been developed in a system of chicken embryo fibroblast cells and cloned Rous sarcoma virus DNA by using a polycation reagent as a mediator to adsorb DNA to the cell surface and dimethyl
E2F1 modulates p38 MAPK phosphorylation via transcriptional regulation of ASK1 and Wip1.
Hershko T
The Journal of Biological Chemistry, 281, 31309-31309 (2006)
Molecular pathways regulating pro-migratory effects of Hedgehog signaling.
Hochman E et al.
The Journal of Biological Chemistry, 281, 33860-33860 (2006)
Gaetana Restivo et al.
Nature communications, 8(1), 1988-1988 (2017-12-08)
Cutaneous melanoma represents the most fatal skin cancer due to its high metastatic capacity. According to the "phenotype switching" model, the aggressive nature of melanoma cells results from their intrinsic potential to dynamically switch from a high-proliferative/low-invasive to a low-proliferative/high-invasive
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