P4380
Protamine sulfate
powder
Sinónimos:
Salmine, Salmine from salmon
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About This Item
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Nombre del producto
Protamine sulfate salt from salmon, Grade II
origen biológico
fish (salmon)
Nivel de calidad
tpo
Grade II
Formulario
powder
color
white to off-white
solubilidad
6 M HCl: 25 mg/mL, clear, colorless to light yellow
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Descripción general
Protamine sulfate (PS), a polycationic, positively charged protein is mostly made up of poly(l-arginine). It is obtained from salmon sperm protein.
Aplicación
Protamine sulfate salt from salmon has been used in the generation of protamine silica nanocomposites.
May be used for the removal of DNA from protein samples or for the purification of DNA binding proteins. It may be used as an alternative to polybrene in retroviral-mediated gene transfer.
Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Acciones bioquímicas o fisiológicas
Protamine sulfate is highly preferred in cardiovascular surgical procedures to reverse the anticoagulant properties of heparin. It is used for biomedical and biotechnological applications due to its biodegradablity.
Protamine sulfate is a small cationic protein that binds and precipitates DNA. Neutralizes the anticoagulant activity of heparin. Inhibits lipoprotein lipase.
Calidad
May contain insolubles as well as histones.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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