P7762

Poly-L-arginine hydrochloride

mol wt 15,000-70,000

• Sinónimos: L-Arginine homopolymer hydrochloride
• Número de CAS: 26982-20-7
• Número MDL: MFCD00166393
• Código UNSPSC: 12352209
• ID de la sustancia en PubChem: 24898874
• NACRES: NA.26

Propiedades

• formulario: powder
• Nivel de calidad: 200
• mol peso: 15,000-70,000
• color: white to off-white
• aplicaciones: cell analysis
• temp. de almacenamiento: −20°C
• cadena SMILES: Cl.NC(CCCNC(N)=N)C(O)=O
• InChI: 1S/C18H38N12O4.ClH/c19-10(4-1-7-26-16(20)21)13(31)29-11(5-2-8-27-17(22)23)14(32)30-12(15(33)34)6-3-9-28-18(24)25;/h10-12H,1-9,19H2,(H,29,31)(H,30,32)(H,33,34)(H4,20,21,26)(H4,22,23,27)(H4,24,25,28);1H/t10-,11-,12-;/m0./s1
• Clave InChI: PQEISBBDIRAKGR-LFELFHSZSA-N

Descripción

Descripción general

Poly-L-arginine hydrochloride (PLA) is a homopolyamino acid. PLA enhances membrane permeability compared to poly-L-lysine. It has applications as drug carrier, neuroprotective agent and in anticancer vaccines preparations. Peptide vaccines in conjugation with PLA promotes antigen-presenting cells (APCs) to generate T cell and elicit immunostimulant functionality.

Aplicación

Poly-L-arginine hydrochloride has been used:

• to generate complex with stimulatory RNA isRNA9.2 as in neutrophils
• used in ribosomal RNA transfection into human monocytic THP-1 cells
• for coating alginate capsule beads

Calidad

Contains 3% or less ornithine residue.

Nota de análisis

Molecular weight based on viscosity of precursor poly-L-ornithine. Also assayed by MALLS.

Otras notas

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)