G2785

Glycitein

≥97% (HPLC)

• Sinónimos: 4′,7-Dihydroxy-6-methoxyisoflavone, Glycetein
• Fórmula empírica (notación de Hill): C₁₆H₁₂O₅
• Número de CAS: 40957-83-3
• Peso molecular: 284.26
• Número MDL: MFCD00016679
• Código UNSPSC: 41106305
• ID de la sustancia en PubChem: 329799906
• NACRES: NA.51

Propiedades

• origen biológico: synthetic (organic)
• Análisis: ≥97% (HPLC)
• formulario: powder
• solubilidad: DMF: 1 mg/mL, clear, colorless to faintly yellow
• temp. de almacenamiento: −20°C
• cadena SMILES: COc1cc2C(=O)C(=COc2cc1O)c3ccc(O)cc3
• InChI: 1S/C16H12O5/c1-20-15-6-11-14(7-13(15)18)21-8-12(16(11)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3
• Clave InChI: DXYUAIFZCFRPTH-UHFFFAOYSA-N

Descripción

Aplicación

Glycitein has been used as standard for the analysis of soy isoflavones and metabolites in urine. It has also been used to bind to recombinant estrogen and progesterone receptors to know the relative binding affinity (RBA) for detection of potential endocrine disruptors.

Acciones bioquímicas o fisiológicas

Glycitein is a soybean (yellow cultivar) isoflavonoid; its natural glycosides are synergistic with genistein in inducing specific gene expression. Glycitein may be used to study anti-oxidation processes at the level of gene transcription where it increases the binding of transcription factors [nuclear factor-E2-related factor 2 (Nrf2) and c-Jun] to the antioxidant response element (ARE) on HO-1 and NQO1 promoters. Glycitein may be used in combination with other isoflavonoids such as genistein and daidzein to study apoptosis.

Glycitein possesses weak estrogenic activity than other soy isoflavones.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)