Saltar al contenido
Merck
Todas las fotos(3)

Key Documents

View All Documentation

F0752

Sigma-Aldrich

D-Fructose 1,6-bisphosphate tetra(cyclohexylammonium) salt

≥95% anhydrous basis (enzymatic)

Sinónimos:

D(+)Fructofuranose 1,6-diphosphate, Harden-Young ester, Hexose diphosphate

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(3)

About This Item

Fórmula empírica (notación de Hill):
C6H14O12P2 · 4C6H13N
Número de CAS:
103213-44-1
Peso molecular:
736.81
Código UNSPSC:
12352201
ID de la sustancia en PubChem:
329799667
NACRES:
NA.25

origen biológico

synthetic (organic)

Nivel de calidad

200

Análisis

≥95% anhydrous basis (enzymatic)

formulario

powder

impurezas

Hexose monophosphates, essentially free

color

white to off-white

solubilidad

water: 100 mg/mL, clear to hazy, colorless to faintly yellow

temp. de almacenamiento

−20°C

cadena SMILES

NC1CCCCC1.NC2CCCCC2.NC3CCCCC3.NC4CCCCC4.O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)C(=O)COP(O)(O)=O

InChI

1S/4C6H13N.C6H14O12P2/c4*7-6-4-2-1-3-5-6;7-3(1-17-19(11,12)13)5(9)6(10)4(8)2-18-20(14,15)16/h4*6H,1-5,7H2;3,5-7,9-10H,1-2H2,(H2,11,12,13)(H2,14,15,16)/t;;;;3-,5-,6-/m....1/s1

Clave InChI

NVWGDAYGDKPKLQ-CBCSRFDDSA-N

Aplicación

D-Fructose-1,6-bisphosphate (FBP) may be used as an allosteric activator of enzymes such as pyruvate kinase and NAD+-dependent L-(+)-lactate dehydrogenase, as an inhibitor of acetate kinase and as a substrate to identify and characterize enzymes such as fructose-1,6-bisphosphate aldolase(s) and fructose-1, 6-bisphosphatase(s). FBP is studied as a neuroprotective agent in brain injury.

Acciones bioquímicas o fisiológicas

D-Fructose-1,6-bisphosphate (FBP), a common metabolic sugar, is the precursor of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate in the glycolytic pathway.

Otras notas

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Los clientes también vieron

Slide 1 of 3

1 of 3

L-Lactate Dehydrogenase (L-LDH)

Roche

LLDH-RO

L-Lactate Dehydrogenase (L-LDH)

D-(−)-Fructose ≥99% (HPLC)

Sigma-Aldrich

F0127

D-(−)-Fructose

Base Trizma® Primary Standard and Buffer, ≥99.9% (titration), crystalline

Sigma-Aldrich

T1503

Base Trizma®

Scott D Pegan et al.
Journal of molecular biology, 386(4), 1038-1053 (2009-01-27)
Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), currently infects one-third of the world's population in its latent form. The emergence of multidrug-resistant and extensive drug-resistant strains has highlighted the need for new pharmacological targets within M. tuberculosis. The class
Chao Wang et al.
Molecular biology reports, 39(4), 5017-5024 (2011-12-14)
This study investigated whether there were single nucleotide polymorphisms (SNPs) in fructose-1,6-bisphosphate aldolase (FBA) gene associated with growth traits of the clam Meretrix meretrix. A FBA gene was identified in M. meretrix and its deduced amino acid residues shared high
Javier Modrego et al.
Journal of vascular surgery, 55(4), 1124-1133 (2012-01-10)
The purpose of this study was to evaluate the expression of proteins related to cytoskeleton and energetic metabolism at abdominal aortic aneurysm (AAA) sites using proteomics. Several remodeling-related mechanisms have been associated with AAA formation but less is known about
Paul D van Poelje et al.
Handbook of experimental pharmacology, 203(203), 279-301 (2011-04-13)
Fructose-1,6-bisphosphatase (FBPase), a rate-controlling enzyme of gluconeogenesis, has emerged as an important target for the treatment of type 2 diabetes due to the well-recognized role of excessive endogenous glucose production (EGP) in the hyperglycemia characteristic of the disease. Inhibitors of
Paul D van Poelje et al.
Diabetes, 55(6), 1747-1754 (2006-05-30)
Gluconeogenesis is increased in type 2 diabetes and contributes significantly to fasting and postprandial hyperglycemia. We recently reported the discovery of the first potent and selective inhibitors of fructose 1,6-bisphosphatase (FBPase), a rate-controlling enzyme of gluconeogenesis. Herein we describe acute
Ver todos los artículos relacionados

Artículos

Glycolysis via the Embden-Meyerhof-Parnas glycolytic pathway

Review the 10 steps of glycolysis in the Embden-Meyerhof-Parnas glycolytic pathway. Easily compare reaction stages and buy the enzymes for your life science research.

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico