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F1502

Sigma-Aldrich

D-Fructose 6-phosphate dipotassium salt

≥97% (enzymatic), amorphous powder

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About This Item

Fórmula lineal:
C6H11O9PK2
Número de CAS:
103213-47-4
Peso molecular:
336.32
Número MDL:
MFCD30342368
Código UNSPSC:
12352201
ID de la sustancia en PubChem:
24894770
NACRES:
NA.25

origen biológico

synthetic (inorganic)

Nivel de calidad

200

Ensayo

≥97% (enzymatic)

Formulario

amorphous powder

impurezas

≤0.05 mol % fructose 1,6-diphosphate
≤1.5 mol % glucose 6-phosphate

color

white to off-white

solubilidad

H2O: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow

trazas de catión

K: 20.3-26.2% (dry basis)

temp. de almacenamiento

−20°C

cadena SMILES

[K+].[K+].OCC1(O)O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@@H]1O

InChI

1S/C6H13O9P.2K/c7-2-6(10)5(9)4(8)3(15-6)1-14-16(11,12)13;;/h3-5,7-10H,1-2H2,(H2,11,12,13);;/q;2*+1/p-2/t3-,4-,5+,6?;;/m1../s1

Clave InChI

UNAFCPBHNZYEIY-UHOQFTJOSA-L

Categorías relacionadas

Aplicación

D-Fructose 6-phosphate (F6P) is a sugar intermediate of the glycolytic pathway that may be used to help identify, differentiate and characterize enzymes such as phosphofructokinase(s), pyrophosphate-dependent fructose-6-phosphate 1-phosphotransferase(s), D-fructose-6-phosphate aldolase(s), glutamine:fructose-6-phosphate amino-transferase(s) and glucosamine-6P synthase(s).

Otras notas

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
SLCJ4907
SLCG2953
SLCC9503
SLBR9491V
SLBM9441V

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Chia-I Lin et al.
Journal of the American Chemical Society, 136(3), 906-909 (2014-01-02)
Lincomycin A is a clinically useful antibiotic isolated from Streptomyces lincolnensis. It contains an unusual methylmercapto-substituted octose, methylthiolincosamide (MTL). While it has been demonstrated that the C8 backbone of MTL moiety is derived from D-fructose 6-phosphate and D-ribose 5-phosphate via
Joel L Asenjo et al.
Biochimica et biophysica acta, 1840(6), 1798-1807 (2014-01-22)
Fructose-1,6-bisphosphatase, a major enzyme of gluconeogenesis, is inhibited by AMP, Fru-2,6-P2 and by high concentrations of its substrate Fru-1,6-P2. The mechanism that produces substrate inhibition continues to be obscure. Four types of experiments were used to shed light on this:
Sławomir Milewski
Biochimica et biophysica acta, 1597(2), 173-192 (2002-06-05)
L-Glutamine: D-fructose-6-phosphate amidotransferase, known under trivial name of glucosamine-6-phosphate synthase, as the only member of the amidotransferase subfamily of enzymes, does not display any ammonia-dependent activity. This enzyme, catalysing the first committed step in a pathway leading to the eventual
Yimin Qian et al.
Bioorganic & medicinal chemistry letters, 21(21), 6264-6269 (2011-10-01)
Through high throughput screening and subsequent hit identification and optimization, we synthesized a series of 1-arylcarbonyl-6,7-dimethoxyisoquinoline derivatives as the first reported potent and reversible GFAT inhibitors. SAR studies of this class of compounds indicated significant impact on GFAT inhibition potency
Philippe Durand et al.
Archives of biochemistry and biophysics, 474(2), 302-317 (2008-02-19)
L-Glutamine:d-fructose-6-phosphate amidotransferase, also known as glucosamine-6-phosphate synthase (GlcN6P synthase), which catalyzes the first step in a pathway leading to the formation of uridine 5'-diphospho-N-acetyl-d-glucosamine (UDP-GlcNAc), is a key point in the metabolic control of the biosynthesis of amino sugar-containing macromolecules.
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