D0184

2′-Deoxyuridine 5′-triphosphate sodium salt solution

100 mM in H₂O

• Sinónimos: dUTP sodium salt
• Fórmula empírica (notación de Hill): C₉H₁₅N₂O₁₄P₃ · xNa⁺
• Número de CAS: 94736-09-1
• Peso molecular: 468.14 (free acid basis)
• Número MDL: MFCD01630759
• Código UNSPSC: 41106305
• ID de la sustancia en PubChem: 24893218
• NACRES: NA.52

Propiedades

• Análisis: ≥99%
• formulario: liquid
• concentración: 100 mM in H₂O
• color: colorless
• actividad extraña: DNase, RNase, none detected
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• cadena SMILES: [Na].OC1CC(OC1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H15N2O14P3.Na.H/c12-5-3-8(11-2-1-7(13)10-9(11)14)23-6(5)4-22-27(18,19)25-28(20,21)24-26(15,16)17;;/h1-2,5-6,8,12H,3-4H2,(H,18,19)(H,20,21)(H,10,13,14)(H2,15,16,17);;
• Clave InChI: FVFWWPFKJNTHIQ-UHFFFAOYSA-N

Descripción

Descripción general

2′-Deoxyuridine 5′-triphosphate (dUTP) is incorporated into DNA during DNA synthesis. It is one of the main intermediate during pyrimidine nucleotide biosynthesis. It is one of the sources of uracil in DNA. Deoxyuridine 5′-triphosphate nucleotidohydrolase suppresses the incorporation of dUTP into DNA. It converts dUTP to 2′-deoxyuridine 5′-monophosphate (dUMP).

Aplicación

2′-Deoxyuridine 5′-triphosphate sodium salt solution has been used in the mouse genomic DNA amplification by polymerase chain reaction (PCR). It is also suitable for conjunction with uracil DNA glycosylase to prevent carryover contamination in PCR. The dUTP is substituted for dTTP in the PCR reaction.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable