C9426

3-[(3-Colamidopropil)dimetilamonio]-1-propanosulfonato hydrate

BioReagent, suitable for electrophoresis, ≥98% (HPLC)

• Sinónimos: CHAPS
• Fórmula empírica (notación de Hill): C₃₂H₅₈N₂O₇S · xH₂O
• Número de CAS: 331717-45-4
• Peso molecular: 614.88 (anhydrous basis)
• Número MDL: MFCD00012116
• Código UNSPSC: 12161902
• ID de la sustancia en PubChem: 24892997
• NACRES: NB.22

Propiedades

• descripción: zwitterionic
• Nivel de calidad: 200
• Línea del producto: BioReagent
• Ensayo: ≥98% (HPLC)
• Formulario: powder
• mol peso: 614.88 g/mol (anhydrous basis)
• técnicas: electrophoresis: suitable; protein quantification: suitable
• impurezas: <0.04% DMF
• mp: 157 °C (dec.) (lit.)
• solubilidad: water: 50 mg/mL, clear, colorless
• idoneidad: suitable for electrophoresis
• temp. de almacenamiento: room temp
• cadena SMILES: O.C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
• InChI: 1S/C32H58N2O7S.H2O/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36;/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41);1H2/t21-,22+,23-,24-,25+,26+,27-,28+,30+,31+,32-;/m1./s1
• Clave InChI: SJCUTFKCLFLIFE-JWTJKVBLSA-N

Descripción

Descripción general

CHAPS is a non-denaturing, zwitterionic sulfobetaine detergent. It is mild and solubilizes membrane proteins and receptors. It is useful for breaking protein-protein interactions. It is a derivative of the naturally occurring bile salts. It has small micellar molecular weight (6,150) and high critical micellar concentration (6 - 10 mM) allowing it to be removed from samples by dialysis.

Aplicación

CHAPS has been used:

• For membrane permeabilization of cells
• As a component in lysis buffer for homogenization of liver tissues as well as adipose tissue
• As a component in denaturing buffer in enzyme characterization
• As a component of 2D- sample buffer in 2D electrophoresis
• For protein solubilization in isoelectric focusing

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302
• Consejos de prudencia: P264 - P270 - P301 + P312 - P501
• Clasificaciones de peligro: Acute Tox. 4 Oral
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable