S3523

Surfactin

from Bacillus subtilis, ≥98.0% (HPLC)

• Sinónimos: surfactin C
• Fórmula empírica (notación de Hill): C₅₃H₉₃N₇O₁₃
• Número de CAS: 24730-31-2
• Peso molecular: 1036.34
• Código UNSPSC: 51102829
• ID de la sustancia en PubChem: 24899562
• NACRES: NA.85

Propiedades

• origen biológico: Bacillus subtilis
• Nivel de calidad: 200
• descripción: zwitterionic
• Análisis: ≥98.0% (HPLC)
• formulario: powder
• condiciones de almacenamiento: (Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
• color: white to faint yellow
• CMC: 7.5-20 μmol/L (depending on methods)
• solubilidad: ethanol: soluble 10 mg/mL
• espectro de actividad antibiótica: Gram-negative bacteria; Gram-positive bacteria; fungi; mycoplasma; neoplastics; viruses
• Modo de acción: cell membrane | interferes
• temp. de almacenamiento: 2-8°C
• cadena SMILES: CC(C)CCCCCCCCC[C@@H]1CC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O1
• InChI: 1S/C53H93N7O13/c1-30(2)20-18-16-14-13-15-17-19-21-36-28-43(61)54-37(22-23-44(62)63)47(66)55-38(24-31(3)4)48(67)57-40(26-33(7)8)51(70)60-46(35(11)12)52(71)58-41(29-45(64)65)50(69)56-39(25-32(5)6)49(68)59-42(27-34(9)10)53(72)73-36/h30-42,46H,13-29H2,1-12H3,(H,54,61)(H,55,66)(H,56,69)(H,57,67)(H,58,71)(H,59,68)(H,60,70)(H,62,63)(H,64,65)/t36-,37+,38+,39-,40-,41+,42+,46+/m1/s1
• Clave InChI: NJGWOFRZMQRKHT-WGVNQGGSSA-N

Descripción

Descripción general

Chemical structure: peptide

Aplicación

Surfactin is used as a surfactant to mediate flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. It is also used to study antitumor activity, activity against enveloped viruses, activity against the protoplast of Bacillus megaterium and the activity against Mycoplasma.

Acciones bioquímicas o fisiológicas

Surfactin is a lipopeptide antibiotic that is composed of one β-hydroxy fatty acid, which has a long fatty acid moiety, and seven amino acids. Three of them have D configurations. It is a powerful biosurfactant that causes lysis of erythrocytes and bacteria. It is also a clotting inhibitor. Surfactin is thought to disrupt or disintegrate membranes via physicochemical interaction with the membranes.

Otras notas

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)