82669

1-Pyrenebutyric hydrazide

for fluorescence, ≥97.0% (T)

• Sinónimos: 4-(1-Pyrenyl)butyric hydrazide
• Fórmula empírica (notación de Hill): C₂₀H₁₈N₂O
• Número de CAS: 55486-13-0
• Peso molecular: 302.37
• Número MDL: MFCD00467260
• Código UNSPSC: 12352125
• ID de la sustancia en PubChem: 329769260
• NACRES: NA.32

Propiedades

• grado: for fluorescence
• Análisis: ≥97.0% (T)
• formulario: solid
• mp: 167-171 °C
• cadena SMILES: NNC(=O)CCCc1ccc2ccc3cccc4ccc1c2c34
• InChI: 1S/C20H18N2O/c21-22-18(23)6-2-3-13-7-8-16-10-9-14-4-1-5-15-11-12-17(13)20(16)19(14)15/h1,4-5,7-12H,2-3,6,21H2,(H,22,23)
• Clave InChI: SOPPDVMSOKMZOC-UHFFFAOYSA-N

Descripción

Descripción general

1-Pyrenebutyric hydrazide (PBH) finds biological/medical applications in the detection, labeling, and quantification of biological carbonyl compounds including aldehydes and/or ketones and carboxylic acids. It is also industrially used in chemo-sensor materials, lubricants, etc.

Aplicación

1-Pyrenebutyric hydrazide may be used as a fluorescence derivatization reagent in the following:

• Determination of succinylacetone (SA) in urine samples of hepatorenal tyrosinemia patients using high-pressure liquid chromatography with fluorescence detection (HPLC-FLD).
• Determination of glutaric and 3-hydroxyglutaric acids in urine of glutaric acidemia type I patients using HPLC technique with intramolecular excimer-forming fluorescence derivatization.

Otras notas

Fluorescent labeling reagent for carbonyl compounds, e.g. cyclobutanones formed on food irradiation; Labeling of other compounds

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302 + H312 + H332,H315,H319,H335
• Consejos de prudencia: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órganos de actuación: Respiratory system
• Código de clase de almacenamiento: 13 - Non Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves