27029

Colato de sodio hydrate

≥97.0% (dried material, NT)

• Sinónimos: Ácido 3α,7α, 12α-trihidroxi-5β-colan-24-oico sodium salt, Ácido colálico sodium salt
• Fórmula empírica (notación de Hill): C₂₄H₃₉NaO₅ · xH₂O
• Número de CAS: 206986-87-0
• Peso molecular: 430.55 (anhydrous basis)
• Beilstein: 3582354
• Número CE: 206-643-5
• Número MDL: MFCD00150749
• Código UNSPSC: 12161900
• ID de la sustancia en PubChem: 57648188
• NACRES: NA.25

Propiedades

• descripción: anionic
• Nivel de calidad: 200
• Análisis: ≥97.0% (dried material, NT)
• formulario: powder
• actividad óptica: [α]20/D +36±2°, c = 0.6% in ethanol (dry matter)
• mol peso: micellar avg mol wt 900-1300
• número de agregación: 2-3
• pérdida: ≤5% loss on drying
• CMC: 9-15 mM (20-25°C)
• solubilidad: H₂O: 0.1 M; H₂O: 100 mg/mL
• HLB: 18
• cadena SMILES: O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C
• InChI: 1S/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1
• Clave InChI: MUVVIYFKOVLQHL-RCVKHMDESA-M

Descripción

Descripción general

Sodium cholate hydrate is a bio-surfactant which can be used as a reducing reagent in aqueous solution.

Sodium cholate hydrate is a non-denaturing, anionic detergent.

Aplicación

• Optimization in Transdermal Drug Delivery: Applied in the formulation of ultra-elastic nanovesicles, sodium cholate hydrate enhances the bioavailability and anti-inflammatory efficacy of deflazacort, demonstrating its potential in transdermal drug delivery systems, which can be adapted for diagnostic purposes (Ali et al., 2021).


• Nanocarrier Formulations for IVDs: The study utilizes sodium cholate hydrate in the surface modification of bilosomes, serving as a functional and biocompatible nanocarrier for hybrid compounds, a method applicable to the formulation of innovative IVD reagents (Waglewska et al., 2020).


• IVD Reagent Formulation for Skin Delivery: Sodium cholate hydrate is featured in the development of nano-transfersomes for the delivery of antioxidants, showcasing its role in creating skin-applied diagnostic reagents that offer antioxidant and anti-aging effects (Avadhani et al., 2017).


• Sorting and Separation Techniques in Nanotechnology: Demonstrating the affinity-mediated sorting order reversal, sodium cholate hydrate is critical in density gradient ultracentrifugation techniques, highlighting its utility in the precise sorting and preparation of materials for diagnostic assays (Jang et al., 2016).

Información de seguridad

• Frases de peligro: H412
• Consejos de prudencia: P273 - P501
• Clasificaciones de peligro: Aquatic Chronic 3
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)