D6750

Sodium deoxycholate

≥97% (titration)

• Sinónimos: 3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt, Desoxycholic acid sodium salt
• Fórmula empírica (notación de Hill): C₂₄H₃₉NaO₄
• Número de CAS: 302-95-4
• Peso molecular: 414.55
• Beilstein: 3581950
• Número CE: 206-132-7
• Número MDL: MFCD00064139
• Código UNSPSC: 12161900
• ID de la sustancia en PubChem: 24894044
• NACRES: NA.21

Propiedades

• descripción: anionic
• Nivel de calidad: 200
• Análisis: ≥97% (titration)
• formulario: powder
• mol peso: micellar avg mol wt 1200-5000
• número de agregación: 3-12
• CMC: 2-6 mM (20-25°C)
• solubilidad: water: 50 mg/mL, clear, colorless to light yellow
• HLB: 16
• grupo funcional: carboxylic acid
• Condiciones de envío: ambient
• temp. de almacenamiento: room temp
• cadena SMILES: [Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
• InChI: 1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1
• Clave InChI: FHHPUSMSKHSNKW-SMOYURAASA-M

Descripción

Descripción general

Deoxycholic acid sodium salt, also known as Sodium Deoxycholate, is a highly versatile ionic detergent utilized for its exceptional ability to solubilize membrane-bound proteins and lyse cells. Its mechanism involves disrupting cell membranes and dissolving hydrophobic molecules, making it an invaluable reagent in scientific research applications. In protein research, it plays a pivotal role in solubilizing proteins, particularly those embedded in membranes, enabling their extraction, purification, and subsequent analysis.

Moreover, Sodium Deoxycholate extends its utility to nucleic acid extraction from cells and tissues. By lysing cells and disrupting cellular structures, it facilitates the release and purification of nucleic acids, proving valuable in cell biology and biochemical research. Beyond these applications, its effectiveness in cell lysis processes positions it as a valuable tool for breaking down cells and releasing their contents, finding applications in diverse biological studies, encompassing microscopy, cell biology, and biochemical research.

Aplicación

Sodium deoxycholate has been used in the lysis buffer prepared for brown adipose tissue. It has been used in the decellularization of aortic valvular conduit.

Acciones bioquímicas o fisiológicas

Solubilizes fats for absorption in the intestines.

Características y beneficios

Highly versatile surfactant for your cell biology and biochemical research

Otras notas

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

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Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302
• Consejos de prudencia: P264 - P270 - P301 + P312 - P501
• Clasificaciones de peligro: Acute Tox. 4 Oral
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves