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Key Documents

255M-1

Sigma-Aldrich

Galectin-3 (9C4) Mouse Monoclonal Antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

100
500

conjugado

unconjugated

forma del anticuerpo

culture supernatant

tipo de anticuerpo

primary antibodies

clon

9C4, monoclonal

descripción

For In Vitro Diagnostic Use in Select Regions (See Chart)

formulario

buffered aqueous solution

reactividad de especies

human

envase

vial of 0.1 mL concentrate (255M-14)
vial of 0.5 mL concentrate (255M-15)
bottle of 1.0 mL predilute (255M-17)
vial of 1.0 mL concentrate (255M-16)
bottle of 7.0 mL predilute (255M-18)

fabricante / nombre comercial

Cell Marque™

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

isotipo

IgG1

control

papillary carcinoma of thyroid

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

visualización

cytoplasmic, nuclear

Información sobre el gen

human ... LGALS3(3958)

Categorías relacionadas

Descripción general

Galectin-3 is a 31 kD beta-galactosidase binding lectin. It has been associated with binding to the basement membrane glycoprotein laminin. Anti-Galectin-3 has been demonstrated to be valuable in differentiating between benign and malignant thyroid neoplasms in both histologic sections and fine needle aspiration biopsy material. Anti-Galectin-3 antibody has also been useful in identifying anaplastic large cell lymphoma.

Calidad


IVD
IVD
IVD
RUO

Ligadura / enlace

Galectin-3 Positive Control Slides, Product No. 255S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Otras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Información legal

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

F Orlandi et al.
Cancer research, 58(14), 3015-3020 (1998-07-29)
Galectin-3 is a carbohydrate-binding protein endowed with an affinity for beta-galactosides. It has been shown to play an important role in cell-cell and cell-matrix interactions and in pre-mRNA splicing. Furthermore, it is involved in the control of cell growth, neoplastic
Mauro Papotti et al.
European journal of endocrinology, 147(4), 515-521 (2002-10-09)
Cystic thyroid lesions can harbour an occult papillary carcinoma, which fine needle aspiration (FNA) biopsy may fail to detect. Recently, new markers such as galectin-3 lectin have been proposed to distinguish benign from malignant thyroid lesions of follicular origin. The
Marille E Herrmann et al.
Archives of pathology & laboratory medicine, 126(6), 710-713 (2002-05-30)
The expression of galectin-3, a human lectin, has been shown to be highly associated with malignant behavior of thyroid lesions. We studied the immunohistochemical expression pattern of galectin-3 in a variety of follicular-derived thyroid lesions (13 benign and 62 malignant)
A Gasbarri et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 17(11), 3494-3502 (1999-11-05)
Thyroid cancer is the most frequently occurring endocrine malignancy; however, preoperative diagnosis of some lesions, in particular those with follicular histology, is difficult, and a consistent number of not otherwise-specified "follicular nodules" are surgically resected more for diagnosis than therapeutic
A Bartolazzi et al.
Lancet (London, England), 357(9269), 1644-1650 (2001-06-27)
Thyroid cancer is the most common endocrine malignant disease, but preoperative diagnosis remains a challenge. Fine-needle aspiration cytology has greatly improved the clinical management of thyroid nodules, but the preoperative characterisation of follicular lesions is very difficult. Many patients are
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