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Merck
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Key Documents

130M-9

Sigma-Aldrich

CD30 (Ber-H2) Mouse Monoclonal Antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

100
500

conjugado

unconjugated

forma del anticuerpo

culture supernatant

tipo de anticuerpo

primary antibodies

clon

Ber-H2, monoclonal

descripción

For In Vitro Diagnostic Use in Select Regions (See Chart)

formulario

buffered aqueous solution

reactividad de especies

human

envase

vial of 0.1 mL concentrate (130M-94)
vial of 0.5 mL concentrate (130M-95)
bottle of 1.0 mL predilute (130M-97)
vial of 1.0 mL concentrate (130M-96)
bottle of 7.0 mL predilute (130M-98)

fabricante / nombre comercial

Cell Marque™

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

isotipo

IgG1κ

control

classic Hodgkin lymphoma

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

visualización

membranous

Información sobre el gen

human ... TNFRSF8(943)

Descripción general

Anti-CD30 detects a formalin-resistant epitope that is expressed by Reed-Sternberg cells in classic Hodgkin lymphoma, the majority of anaplastic large cell lymphomas, primary cutaneous CD30 positive T-cell lymphoproliferative disorders, and in embryonal carcinomas. Occasionally diffuse large B-cell lymphoma stains with this antibody. This antibody also stains plasma cells in paraffin-embedded tissue. However, reactive immunoblasts are immunoreactive with this antibody. The staining pattern of anti-CD30 in lymphoma or embryonal carcinoma is different, with the former being membranous and exhibiting Golgi zone accentuation in location, and the latter being membranous only.

Calidad


IVD
IVD
IVD
RUO

Ligadura / enlace

CD30 Positive Control Slides, Product No. 130S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Otras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Información legal

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Visite la Librería de documentos

Rabban JT, et al.
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications, 702-702 (2014)
David H George et al.
The American journal of surgical pathology, 27(4), 487-493 (2003-03-27)
Anaplastic large cell lymphoma (ALCL) rarely occurs in the central nervous system. Although defined by its composition of large, pleomorphic, CD30-positive lymphocytes, ALCL is heterogeneous. Most are T cell but some are null cell. Most but not all have a
R Schwarting et al.
Blood, 74(5), 1678-1689 (1989-10-01)
The production and characterization of a monoclonal antibody (MoAb) designated Ber-H2, directed against a new epitope of the Ki-1 (CD30) antigen, are described. In comparison with the formerly reported Ki-1 MoAb whose reactivity with Hodgkin and Reed-Sternberg (H-RS) cells in
Cyrus V Hedvat et al.
Human pathology, 33(10), 968-974 (2002-10-24)
The immunohistochemical analysis of lymphoid neoplasms has led to refined classification schemes based on the profile of antigen expression and correlation with morphological, cytogenetic, molecular, and clinical features. Tissue microarrays (TMAs) are a powerful tool to rapidly characterize the phenotypic

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