Saltar al contenido
Merck
Todas las fotos(1)

Key Documents

248M-9

Sigma-Aldrich

Ep-CAM/Epithelial Specific Antigen (Ber-EP4) Mouse Monoclonal Antibody

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

100
500

conjugado

unconjugated

forma del anticuerpo

culture supernatant

tipo de anticuerpo

primary antibodies

clon

Ber-EP4, monoclonal

descripción

For In Vitro Diagnostic Use in Select Regions (See Chart)

formulario

buffered aqueous solution

reactividad de especies

human

envase

vial of 0.1 mL concentrate (248M-94)
vial of 0.5 mL concentrate (248M-95)
bottle of 1.0 mL predilute (248M-97)
vial of 1.0 mL concentrate (248M-96)
bottle of 7.0 mL predilute (248M-98)

fabricante / nombre comercial

Cell Marque™

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

isotipo

IgG1κ

control

colon carcinoma

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

visualización

cytoplasmic

Información sobre el gen

human ... EPCAM(4072)

Descripción general

Epithelial cell adhesion molecule (Ep-CAM) is a transmembrane glycoprotein localized on the membrane of cells in most epithelial tissues. Immunoreactivity with the antibody to E-CAM has been seen in the majority of epithelial neoplasms, whereas most non-epithelial neoplasms do not show Ep-CAM expression. Ep-CAM is not expressed in mesothelial cells, hepatocytes, and lymphocytes. In conjunction with other markers, Ep-CAM can be used as an aid in determining the epithelial origin of neoplasms such as lung adenocarcinoma.

Calidad


IVD
IVD
IVD
RUO

Ligadura / enlace

Ep-CAM Positive Control Slides, Product No. 248S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Otras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Información legal

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

¿No encuentra el producto adecuado?  

Pruebe nuestro Herramienta de selección de productos.

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Nelson G Ordóñez
Advances in anatomic pathology, 13(1), 16-25 (2006-02-08)
At present, a large number of immunohistochemical markers that can be used in the differential diagnosis between epithelioid peritoneal mesotheliomas and serous carcinomas are available. However, great differences of opinion exist regarding the individual value of some of these markers.
N G Ordóñez
American journal of clinical pathology, 109(1), 85-89 (1998-01-14)
Although most studies have indicated that Ber-EP4 immunostaining can assist in differentiating epithelial pleural mesotheliomas from adenocarcinomas that metastasize to the pleura, the percentage of positive cases has varied greatly among different studies. Authors of a recent publication concluded that
Nelson G Ordóñez
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 19(3), 417-428 (2006-01-18)
As both mesotheliomas and squamous carcinomas can present a wide variety of morphological patterns, they can on occasion be confused. Recently, some groups of investigators have called attention to the difficulties that sometimes exist in distinguishing between these malignancies and
C K Ma et al.
American journal of clinical pathology, 99(5), 551-557 (1993-05-01)
Distinguishing primary hepatocellular carcinoma (HCC) from metastatic carcinomas to the liver is often difficult, if not impossible, particularly in needle biopsy and fine-needle aspiration specimens. In an attempt to identify a specific immunohistochemical profile that would distinguish HCC from metastatic
R Carella et al.
The American journal of surgical pathology, 25(1), 43-50 (2001-01-06)
Immunohistochemistry provides an important indicator for differential diagnosis between pleural malignant mesothelioma and lung adenocarcinoma, which have complex therapeutic and medicolegal implications. To pinpoint a reliable, restricted panel of markers, the authors evaluated the efficacy of select commercial antibodies in
Ver todos los artículos relacionados

Contenido relacionado

Diagnostic Immunohistochemistry Procedures

Diagnostic immunohistochemistry overview highlights its importance in cancer diagnosis and detecting infectious diseases in modern clinical pathology.

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico