X4251

XTT sodium salt

analytical standard, ≥90%

• Sinónimos: 2,3-Bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide inner salt
• Fórmula empírica (notación de Hill): C₂₂H₁₆N₇NaO₁₃S₂
• Número de CAS: 111072-31-2
• Peso molecular: 673.52
• Número MDL: MFCD00083517
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329830806
• NACRES: NA.24

Propiedades

• grado: analytical standard
• Nivel de calidad: 100
• Análisis: ≥90%
• técnicas: HPLC: suitable; gas chromatography (GC): suitable
• aplicaciones: forensics and toxicology; pharmaceutical (small molecule)
• formato: neat
• temp. de almacenamiento: 2-8°C
• cadena SMILES: [Na+].COc1cc(c(cc1-n2nc(n[n+]2-c3cc(c(cc3OC)[N+]([O-])=O)S([O-])(=O)=O)C(=O)Nc4ccccc4)S([O-])(=O)=O)[N+]([O-])=O
• InChI: 1S/C22H17N7O13S2.Na/c1-41-17-8-15(28(31)32)19(43(35,36)37)10-13(17)26-24-21(22(30)23-12-6-4-3-5-7-12)25-27(26)14-11-20(44(38,39)40)16(29(33)34)9-18(14)42-2;/h3-11H,1-2H3,(H2-,23,30,35,36,37,38,39,40);/q;+1/p-1
• Clave InChI: JACYMBNQPPWQML-UHFFFAOYSA-M

Descripción

Aplicación

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Useful in AIDS and cancer testing.

XTT has been used in conjunction with phenazine methosulfate (PMS) to screen human cancer cell lines. The tetrazolium dye has also been used to study fungal cell damage, in testing antimicrobial susceptibility of staphylococci, and in Candida biofilm research. Limitations to the XTT assay have been reported.

Principio

In living cells, XTT is metabolically reduced to produce a colorimetric, water-soluble formazan product.

Información de seguridad

• Pictogramas: GHS02
• Palabra de señalización: Danger
• Frases de peligro: H242
• Consejos de prudencia: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Clasificaciones de peligro: Self-react. C
• Riesgos supl.: EUH044
• Código de clase de almacenamiento: 4.1A - Other explosive hazardous materials
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)