PHR1108

L-Histidina

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: NSC 137773, Ácido (S)-2-amino-3-(4-imidazolil)propiónico
• Fórmula empírica (notación de Hill): C₆H₉N₃O₂
• Número de CAS: 71-00-1
• Peso molecular: 155.15
• Beilstein: 84088
• Número CE: 200-745-3
• Número MDL: MFCD00064315
• Código UNSPSC: 41116107
• eCl@ss: 32160406
• ID de la sustancia en PubChem: 329823130
• NACRES: NA.24

Propiedades

• grado: certified reference material; pharmaceutical secondary standard
• Nivel de calidad: 300
• Agency: traceable to Ph. Eur. H0750000; traceable to USP 1308505
• familia API: histidine
• CofA: current certificate can be downloaded
• técnicas: HPLC: suitable; gas chromatography (GC): suitable
• mp: 282 °C (dec.) (lit.)
• aplicaciones: cleaning products; cosmetics; flavors and fragrances; food and beverages; personal care; pharmaceutical (small molecule)
• formato: neat
• temp. de almacenamiento: 2-30°C
• cadena SMILES: N[C@@H](Cc1c[nH]cn1)C(O)=O
• InChI: 1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
• Clave InChI: HNDVDQJCIGZPNO-YFKPBYRVSA-N

Descripción

Descripción general

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. L-Histidine is an essential amino acid, widely present at the active sites of enzymes. It binds to metal ions and may aid in the transport of copper. It also plays an important role for the binding of heme groups, macromolecules and phosphate groups in the binding sites of proteins.

Aplicación

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Acciones bioquímicas o fisiológicas

Precursor de la histamina por medio de la histidina descarboxilasa.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAA7159 in the slot below. This is an example certificate only and may not be the lot that you receive.

Productos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable