H6034

L-Histidina

98.5-101.0%, suitable for cell culture, non-animal source, meets EP, USP testing specifications

• Sinónimos: NSC 137773, Ácido (S)-2-amino-3-(4-imidazolil)propiónico
• Fórmula empírica (notación de Hill): C₆H₉N₃O₂
• Número de CAS: 71-00-1
• Peso molecular: 155.15
• Beilstein: 84088
• Número CE: 200-745-3
• Número MDL: MFCD00064315
• Código UNSPSC: 12352209
• eCl@ss: 32160406
• ID de la sustancia en PubChem: 24895728
• NACRES: NA.26

Propiedades

• product name: L-Histidina, suitable for cell culture, meets EP, USP testing specifications, from non-animal source
• origen biológico: non-animal source
• Agency: meets EP testing specifications; meets USP testing specifications
• Análisis: 98.5-101.0%
• formulario: powder
• actividad óptica: [α]20/D 12.0 to 12.8 °, c = 11 in 6 M HCl; [α]25/D 12.6 to 14.0 °, c = 11 in 6 M HCl
• técnicas: cell culture | mammalian: suitable
• impurezas: endotoxin, tested
• color: white to off-white
• mp: 282 °C (dec.) (lit.)
• solubilidad: H₂O: 50 mg/mL
• trazas de catión: As: ≤1 ppm; Fe: ≤10 ppm; NH₄⁺: <0.02%
• aplicaciones: peptide synthesis; pharmaceutical (small molecule)
• grupo funcional: (Imidazole); amine; carboxylic acid
• temp. de almacenamiento: room temp
• cadena SMILES: N[C@@H](Cc1c[nH]cn1)C(O)=O
• InChI: 1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
• Clave InChI: HNDVDQJCIGZPNO-YFKPBYRVSA-N
• Información sobre el gen: human ... CA1(759) , CA2(760)

Descripción

Descripción general

L-Histidine is a proteinogenic amino acid and an essential amino acid required for histamine production. This positively charged amino acid is vital for growth, tissue repair, myelin sheath maintenance, and histamine synthesis. Histamine plays critical roles in immunity, gastric secretion, and more. L-Histidine is essential for blood cell production and tissue protection against radiation and heavy metals. L-Histidine plays a role as a metabolite and also acts as a cofactor in enzyme protection during protein synthesis. It is an L-enantiomer of histidine and is necessary for histamine synthesis and human development. L-Histidine finds applications in cell culture, metabolomics and biochemical research.

Aplicación

L-histidine has been used as a component in agar plates containing 5-fluorocytosine (5-FC) for the selection of yeast transformants. It has also been used as a component of adult mouse keratinocyte growth medium.

Acciones bioquímicas o fisiológicas

L-Histidine is an essential amino acid that binds to metal ions and may aid in the transport of copper. Histidine is widely present at the active sites of enzymes. It also has a role in binding of heme groups, macromolecules and phosphate groups in the binding sites of proteins.

Precursor de la histamina por medio de la histidina descarboxilasa.

Características y beneficios

• Can be used in Metabolomics and Biochemical research
• High-quality compound suitable for multiple research applications

Otras notas

For additional information on our range of Biochemicals, please complete this form.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)