939048

Lithium bis(trimethylsilyl)amide ChemBeads

• Sinónimos: Hexamethyldisilazane lithium salt ChemBeads
• Fórmula empírica (notación de Hill): LiC₆H₁₈NSi₂
• Peso molecular: 167.33
• Número MDL: MFCD00008261
• Código UNSPSC: 12352100

Propiedades

• descripción: Organic Salt
• Nivel de calidad: 100
• Formulario: solid
• composición: 14-16 wt% loading of base
• idoneidad de la reacción: core: lithium
• cadena SMILES: [Li]N([Si](C)(C)C)[Si](C)(C)C
• InChI: 1S/C6H18NSi2.Li/c1-8(2,3)7-9(4,5)6;/h1-6H3;/q-1;+1
• Clave InChI: YNESATAKKCNGOF-UHFFFAOYSA-N

Descripción

Descripción general

Lithium bis(trimethylsilyl)amide is a non-nucleophilic strong Brønsted base, which is generally soluble in most of the nonpolar organic solvents. It is most commonly employed in organic reactions.

Aplicación

Base employed in generating enolates for the preparation of lactone precursors, pyranones, and cyclohexanes. Used to catalyze the addition of phosphine P-H bonds to carbodiimides leading to phosphaguanidines.[6] Also used in a novel three-step synthesis of disubstituted 1,2,5-thiadiazoles. For general uses, product is also available in powdered form (324620)

Características y beneficios

ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.

Otras notas

• High-Throughput Reaction Screening with Nanomoles of Solid Reagents Coated on Glass Beads
• Versatile Methods to Dispense Sub-Milligram Quantities of Solids using Chemical Coated Beads for High-Throughout Experimentation
• ChemBead Enabled High-Throughput Cross-Electrophile Coupling Reveals a New Complementary Ligand

Información de seguridad

• Pictogramas: GHS02,GHS05
• Palabra de señalización: Danger
• Frases de peligro: H228,H251,H314
• Consejos de prudencia: P210 - P235 - P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Clasificaciones de peligro: Eye Dam. 1 - Flam. Sol. 1 - Self-heat. 1 - Skin Corr. 1B
• Riesgos supl.: EUH014
• Código de clase de almacenamiento: 4.2 - Pyrophoric and self-heating hazardous materials
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): 62.6 °F - closed cup
• Punto de inflamabilidad (°C): 17 °C - closed cup