78645

Levetiracetam

analytical standard

• Sinónimos: (αS)-α-Ethyl-2-oxo-1-pyrrolidineacetamide, 2(S)-(2-oxopyrrolidin-1-yl)butyramide
• Fórmula empírica (notación de Hill): C₈H₁₄N₂O₂
• Número de CAS: 102767-28-2
• Peso molecular: 170.21
• Número MDL: MFCD03265610
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329768167
• NACRES: NA.24

Propiedades

• grado: analytical standard
• Nivel de calidad: 100
• Ensayo: ≥98.0% (HPLC)
• actividad óptica: [α]/D -90±5°, c = 1 in acetone
• caducidad: limited shelf life, expiry date on the label
• técnicas: HPLC: suitable; gas chromatography (GC): suitable
• aplicaciones: forensics and toxicology; veterinary
• Formato: neat
• cadena SMILES: CC[C@H](N1CCCC1=O)C(N)=O
• InChI: 1S/C8H14N2O2/c1-2-6(8(9)12)10-5-3-4-7(10)11/h6H,2-5H2,1H3,(H2,9,12)/t6-/m0/s1
• Clave InChI: HPHUVLMMVZITSG-LURJTMIESA-N
• Información sobre el gen: human ... CACNA1B(774) , SV2A(9900)

Descripción

Descripción general

Levetiracetam is an orally active antiepileptic drug, having a high therapeutic index and potential antiepileptogenic and anticonvulsant effects.

Aplicación

Levetiracetam may be used as a reference standard in the determination of levetiracetam in biological fluid samples using high-performance liquid chromatography coupled with electrospray tandem mass spectrometry (HPLC-ESI-MS/MS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Acciones bioquímicas o fisiológicas

Levetiracetam is a pyrrolidine with antiepileptic activity. Stereoselective binding of levetiracetam was confined to synaptic plasma membranes in the central nervous system with no binding occurring in peripheral tissue. Levetiracetam inhibits burst firing without affecting normal neuronal excitability, which suggests that it may selectively prevent hyper-synchronization of epileptiform burst firing and propagation of seizure activity.

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Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable