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Merck
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P5295

Sigma-Aldrich

Piracetam

Sinónimos:

2-(2-Oxopyrrolidino)acetamide, 2-Oxo-1-pyrrolidineacetamide

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About This Item

Fórmula empírica (notación de Hill):
C6H10N2O2
Número de CAS:
7491-74-9
Peso molecular:
142.16
Número CE:
231-312-7
Número MDL:
MFCD00079246
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
24278639
NACRES:
NA.77

formulario

powder

cadena SMILES

NC(=O)CN1CCCC1=O

InChI

1S/C6H10N2O2/c7-5(9)4-8-3-1-2-6(8)10/h1-4H2,(H2,7,9)

Clave InChI

GMZVRMREEHBGGF-UHFFFAOYSA-N

Información sobre el gen

human ... GRIA1(2890) , GRIA2(2891) , GRIA3(2892) , GRIA4(2893)
rat ... Gria1(50592)

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Aplicación

Piracetam has been used to study crystal structure and physicochemical properties of six co-crystals of piracetam. It has also been used to study its in vitro antioxidant properties.

Acciones bioquímicas o fisiológicas

Piracetam (2-oxo-1-pyrrolidinyl-acetamide) is a nootropic drug, which enhances memory and facilitates learning. Piracetam also acts as a vasodilator and improves blood flow. It has a potential to treat cognitive impairment in aging, brain injury, memory and balance problems. In addition, piracetam is also used to treat peripheral vascular disease.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Piracetam and vinpocetine ameliorate rotenone-induced Parkinsonism in rats
Zaitone SA, et al.
International Journal of Pharmaceutics, 44(6), 774-774 (2012)
Hélène Amieva et al.
PloS one, 8(1), e52755-e52755 (2013-01-18)
Numerous studies have looked at the potential benefits of various nootropic drugs such as Ginkgo biloba extract (EGb761®; Tanakan®) and piracetam (Nootropyl®) on age-related cognitive decline often leading to inconclusive results due to small sample sizes or insufficient follow-up duration.
Rute A P Costa et al.
European journal of pharmacology, 701(1-3), 82-86 (2013-01-22)
Mitochondrial oxidative stress followed by membrane permeability transition (MPT) has been considered as a possible mechanism for statins cytotoxicity. Statins use has been associated with reduced risk of cancer incidence, especially prostate cancer. Here we investigated the pathways leading to
A H Gouliaev et al.
Brain research. Brain research reviews, 19(2), 180-222 (1994-05-01)
Nearly three decades have now passed since the discovery of the piracetam-like nootropics, compounds which exhibit cognition-enhancing properties, but for which no commonly accepted mechanism of action has been established. This review covers clinical, pharmacokinetic, biochemical and behavioural results presented
H Kažoka et al.
Journal of chromatography. A, 1281, 160-165 (2013-02-12)
High-performance liquid chromatography was used for the enantiomeric separation of two chiral piracetam derivatives. The suitability of six commercially available polysaccharide-based chiral stationary phases (CSPs) under normal phase mode for direct enantioseparation has been investigated. The influence of the CSPs
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