34002

(S)-(−)-Sulpiride

VETRANAL^®, analytical standard

• Sinónimos: (S)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide, Levosulpiride
• Fórmula empírica (notación de Hill): C₁₅H₂₃N₃O₄S
• Número de CAS: 23672-07-3
• Peso molecular: 341.43
• Número MDL: MFCD00055220
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329754747
• NACRES: NA.24

Propiedades

• grado: analytical standard
• Nivel de calidad: 100
• Línea del producto: VETRANAL^®
• caducidad: limited shelf life, expiry date on the label
• técnicas: HPLC: suitable; gas chromatography (GC): suitable
• mp: 183-186 °C (lit.)
• aplicaciones: forensics and toxicology; pharmaceutical (small molecule)
• Formato: neat
• cadena SMILES: CCN1CCC[C@H]1CNC(=O)c2cc(ccc2OC)S(N)(=O)=O
• InChI: 1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1
• Clave InChI: BGRJTUBHPOOWDU-NSHDSACASA-N

Descripción

Descripción general

(S)-(−)-Sulpiride is a levorotatory enantiomer of sulpiride, which shows greater central antidopaminergic activity, antiemetic and antidyspeptic effects. It is also used as a therapeutic drug for the treatment of depression and somatoform disorders.

Aplicación

(S)-(−)-Sulpiride may be used as an analytical reference standard for the determination of the drug, in biological samples using hydrophilic interaction liquid chromatography−tandem mass spectrometry (HILIC−MS/MS) and reversed-phase high-performance liquid chromatography with fluorescence detection (HPLC-FD).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Acciones bioquímicas o fisiológicas

D₂ dopamine receptor antagonist; antipsychotic.

Información legal

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)