32211-M

Cloroformo

puriss. p.a., reag. ISO, reag. Ph. Eur., 99.0-99.4% (GC)

• Sinónimos: Triclorometano, Tricloruro de metilidino
• Fórmula empírica (notación de Hill): CHCl₃
• Número de CAS: 67-66-3
• Peso molecular: 119.38
• Beilstein: 1731042
• Número CE: 200-663-8
• Número MDL: MFCD00000826
• Código UNSPSC: 12191502
• ID de la sustancia en PubChem: 329754102
• NACRES: NA.21

Propiedades

• Agency: USP/NF; reag. ISO; reag. Ph. Eur.
• densidad de vapor: 4.1 (vs air)
• presión de vapor: 160 mmHg ( 20 °C)
• grado: puriss. p.a.
• Análisis: 99.0-99.4% (GC)
• formulario: liquid
• contiene: ~1% ethanol as stabilizer
• técnicas: RNA extraction: suitable
• impurezas: ≤0.00001% free chlorine (Cl); ≤0.00005% free acid (as HCl); ≤0.0005% non-volatile matter; ≤0.005% aldehydes and ketones (as CH₃COCH₃); ≤0.005% carbonyl compounds (as CO); ≤0.01% tetrachloroethene (GC); ≤0.01% tetrachloromethane (GC); ≤0.01% trichloroethene (GC); ≤0.01% water (Karl Fischer); ≤0.03% dichloromethane (GC); 0.6-1.0% ethanol (GC)
• índice de refracción: n20/D 1.445 (lit.)
• bp: 60.5-61.5 °C (lit.)
• mp: −63 °C (lit.)
• densidad: 1.476-1.483 g/mL at 20 °C; 1.492 g/mL at 25 °C (lit.)
• trazas de anión: chloride (Cl^-): ≤0.0001%
• trazas de catión: Al: ≤0.50 ppm; B: ≤0.02 ppm; Ba: ≤0.10 ppm; Ca: ≤0.50 ppm; Cd: ≤0.05 ppm; Co: ≤0.02 ppm; Cr: ≤0.02 ppm; Cu: ≤0.02 ppm; Fe: ≤0.10 ppm; Mg: ≤0.10 ppm; Mn: ≤0.02 ppm; Ni: ≤0.02 ppm; Pb: ≤0.05 ppm; Sn: ≤0.10 ppm; Zn: ≤0.10 ppm
• cadena SMILES: ClC(Cl)Cl
• idoneidad: complies for appearance; complies for reaction against H₂SO₄; complies for suitability of determ. w. dithizone
• InChI: 1S/CHCl3/c2-1(3)4/h1H
• Clave InChI: HEDRZPFGACZZDS-UHFFFAOYSA-N

Descripción

Descripción general

Chloroform, a halogenated hydrocarbon, is widely employed as a solvent. Its photochemical degradation has been investigated in the presence of TiO₂ aqueous suspensions (wavelength range of 310-380nm).

Aplicación

Chloroform may be employed as a solvent for the following studies:

• Extraction of RNA from plant cells.
• Preparation of dioleoylphosphatidylcholine (DOPC) solution.
• Dissolution of 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC).

It may be employed in a rapid quantitative method for the release of periplasmic proteins from bacterial strains.

Chloroform may be used as a solvent to enhance the enantioselectivity of secondary alcohols formed by the borohydride reduction of carbonyl compounds in the presence of optically active ketoiminatocobalt complexes.

Otras notas

For information on chloroform miscibility, please visit the following link:
Chloroform Miscibility/Immiscibility Table

Información de seguridad

• Pictogramas: GHS06,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H302,H315,H319,H331,H336,H351,H361d,H372
• Consejos de prudencia: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Clasificaciones de peligro: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Órganos de actuación: Central nervous system, Liver,Kidney
• Código de clase de almacenamiento: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): does not flash
• Punto de inflamabilidad (°C): does not flash