MABD146

Anti-Lefty Antibody, clone 1G9.1

clone 1G9.1, from mouse

• Sinónimos: Left-right determination factor 1, Left-right determination factor B, Protein lefty-1, Protein lefty-B
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.75

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• forma del anticuerpo: purified antibody
• tipo de anticuerpo: primary antibodies
• clon: 1G9.1, monoclonal
• reactividad de especies: rat, mouse
• técnicas: western blot: suitable
• isotipo: IgMκ
• Nº de acceso NCBI: NP_066277
• Nº de acceso UniProt: O75610
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... LEFTY1(10637)

Descripción

Descripción general

Left-right determination factor 1 (LEFTY1) also known as Left-right determination factor B, Protein lefty-1, Protein lefty-B, and encoded by the gene name LEFTYB, LEFTY1, LEFTB, is a member of the the TGF-beta family. LEFTY1 collaborates with other members of the TGFβ (Transforming Growth Factor) family to establish a left-right axis that dictates the asymmetrical distribution of internal organs during vertebrate embryogenesis. Mice deficient in LEFTY1 are affected by pulmonary isomerism and abnormal placement of vascular tracts, possibly the result of unregulated expression of LEFTY2 and NODAL.

Inmunógeno

KLH-conjugated linear peptide corresponding to human Lefty and spans the pro and mature cleavage sites.

Aplicación

Anti-Lefty Antibody, clone 1G9.1 | MABD146 is an antibody against Lefty Antibody for use in Western Blotting.

Research Category
Stem Cell Research

Research Sub Category
Cell Cycle, DNA Replication & Repair

Western Blotting Analysis: 0.5 µg/mL from a representative lot detected Lefty in 10 µg of C2C12 and NIH-3T3 cell lysate.

Calidad

Evaluated by Western Blotting in L6 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Lefty in 10 µg of L6 cell lysate.

Descripción de destino

~40 kDa observed

Ligadura / enlace

Replaces: MABD186

Forma física

Format: Purified

Purified by Ion-Exchange Chromatography

Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Otras notas

Concentration: Please refer to lot specific datasheet.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable