410225

Glicina

ACS reagent, ≥98.5%

• Sinónimos: Glicocola, Ácido aminoacético, Ácido aminoetanoico
• Fórmula lineal: NH₂CH₂COOH
• Número de CAS: 56-40-6
• Peso molecular: 75.07
• Beilstein: 635782
• Número CE: 200-272-2
• Número MDL: MFCD00008131
• Código UNSPSC: 12352209
• eCl@ss: 32160406
• ID de la sustancia en PubChem: 24865701
• NACRES: NA.21

Propiedades

• grado: ACS reagent
• Nivel de calidad: 200
• Análisis: ≥98.5%
• formulario: powder, crystals or granules
• impurezas: H₂SO₄, passes test (darkened); Hydrolyzable subsances, passes test
• residuo de ign.: ≤0.1%
• color: white
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• mp: 240 °C (dec.) (lit.)
• trazas de anión: chloride (Cl^-): ≤0.005%; sulfate (SO₄^2-): ≤0.005%
• trazas de catión: NH₄⁺: ≤0.005%; heavy metals: ≤0.002% (by ICP)
• aplicaciones: peptide synthesis
• cadena SMILES: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• Clave InChI: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Información sobre el gen: rat ... Grin2a(24409)

Descripción

Descripción general

Glycine is the simplest amino acid building block.

Aplicación

Glycine has been used in whole-cell patch clamp recording to measure inward NMDA (N-methyl-D-aspartate) currents. It has also been used as a model organic system in crystallography to demonstrate a novel acoustic nebulization platform.

Acciones bioquímicas o fisiológicas

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.

Neurotransmisor inhibidor de la médula espinal, regulador alostérico de los receptores NMDA.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)