MAB3502-I

Anti-Angiotensin Converting Enzyme Antibody, clone 2E2

culture supernatant, clone 2E2, from mouse

• Sinónimos: Angiotensin-converting enzyme, ACE, Dipeptidyl carboxypeptidase I, Kininase II, CD143
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• forma del anticuerpo: culture supernatant
• tipo de anticuerpo: primary antibodies
• clon: 2E2, monoclonal
• reactividad de especies: rat
• reactividad de especies (predicha por homología): human (immunogen homology)
• técnicas: western blot: suitable
• isotipo: IgG1
• Nº de acceso NCBI: NP_000780
• Nº de acceso UniProt: P12821
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... ACE(1636)

Descripción

Descripción general

Angiotensin-converting enzyme (ACE) is a zinc-metallopeptidase belonging to the peptidase M2 family. It catalyzes the conversion of angiotensin I to angiotensin II and the degradation of bradykinin, which increases the vasoconstrictive effects of angiotensin. The Angiotensin-converting enzyme plays an important role in maintaining cardiac function and vascular tone. It is highly expressed in the heart, lung, kidney, gastrointestinal system, and prostate. Defects in the Angiotensin-converting may contribute cardiac disease; and renal tubular dysgenesis, a condition characterized by persistent fetal anuria and perinatal death.

Inmunógeno

Human Angiotensin Converting Enzyme.

Aplicación

Anti-Angiotensin Converting Enzyme Antibody, clone 2E2.

Calidad

Evaluated by Western Blot in rat Angiotensin Converting Enzyme.

Western Blot Analysis: A 1:2,000 dilution of this antibody detected rat Angiotensin Converting Enzyme in WB.

Descripción de destino

~180 kDa observed. The calculated molecular weight is 150 kDa; however, this protein is known to be glycolsylated.

Ligadura / enlace

Replaces: MAB3502

Forma física

Mouse monoclonal IgG1 cultured supernatant without preservatives.

Nota de análisis

Control
Rat Angiotensin Converting Enzyme

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable