Saltar al contenido
Merck
Todas las fotos(1)

Documentos clave

MAB2168

Sigma-Aldrich

Anti-Huntingtin Protein Antibody, a.a. 2146-2541, clone HU-2E8

ascites fluid, clone HU-2E8, Chemicon®

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización


About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

forma del anticuerpo

ascites fluid

tipo de anticuerpo

primary antibodies

clon

HU-2E8, monoclonal

reactividad de especies

monkey, human

fabricante / nombre comercial

Chemicon®

técnicas

ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

isotipo

IgG1

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

dry ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

Especificidad

Reacts with Huntingtin protein from human and monkey. Weak to no reactivity with mouse. Has not been tested on other species.

Inmunógeno

Epitope: a.a. 2146-2541
Human huntingtin fragment from aa 2146 to 2541 as a fusion protein.

Aplicación

Anti-Huntingtin Protein Antibody, a.a. 2146-2541, clone HU-2E8 is an antibody against Huntingtin Protein for use in ELISA, WB, IC, IH(P).
ELISA: 1:500-1:5,000

Western blot: 1:500-1:5,000

Immunohistochemistry on frozen and microwave oven treated paraffin sections

(human tissue): 1:500-1:5,000

Immunocytochemistry on transfected cells: 1:500-1:5,000

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases

Forma física

Ascites fluid. Liquid, does not contain any preservative.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

¿No encuentra el producto adecuado?  

Pruebe nuestro Herramienta de selección de productos.

Opcional

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

nwg

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Increased apoptosis, Huntingtin inclusions and altered differentiation in muscle cell cultures from Huntington's disease subjects.
Ciammola, A; Sassone, J; Alberti, L; Meola, G; Mancinelli, E; Russo, MA; Squitieri, F; Silani, V
Cell Death and Differentiation null
Huntingtin distribution among striatal output neurons of normal rat brain
Fusco, F.R. et al.
Neuroscience Letters, 339, 53-56 (2003)
Impaired Ganglioside Metabolism in Huntington's Disease and Neuroprotective Role of GM1.
Maglione V, Marchi P, Di Pardo A, Lingrell S, Horkey M, Tidmarsh E, Sipione S
The Journal of Neuroscience null
Paula A Desplats et al.
Neurobiology of disease, 31(3), 298-308 (2008-07-04)
Transcriptional dysregulation has emerged as a central pathogenic mechanism in Huntington's disease (HD), which is associated with neuropathological changes predominantly in the striatum. Here we demonstrate that expression of Bcl11b (a.k.a. CTIP2), a transcription factor exhibiting highly-enriched localization in adult
F R Fusco et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 19(4), 1189-1202 (1999-02-10)
Immunohistochemistry and single-cell RT-PCR were used to characterize the localization of huntingtin and/or its mRNA in the major types of striatal neurons and in corticostriatal projection neurons in rats. Single-label immunohistochemical studies revealed that striatum contains scattered large neurons rich

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico