GF303
G-CSF Protein, Human Recombinant Animal Free
The GCSF protein is a pleiotropic cytokine best known for its specific effects on the proliferation, differentiation & activation of hematopoietic cells of the neutrophilic granulocyte lineage. Manufactured using all non-animal reagents.
Sinónimos:
GCSF, Granulocyte Colony Stimulating Factor, Pluripoietin, Filgrastim, Lenograstim
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About This Item
Código UNSPSC:
12352202
eCl@ss:
32160405
NACRES:
NA.75
Productos recomendados
Nivel de calidad
Análisis
>98% (SDS-PAGE and HPLC)
impurezas
<0.1 μg/mg protein endotoxin (<1EU/μg)
Nº de acceso NCBI
Nº de acceso UniProt
Condiciones de envío
dry ice
Descripción general
Granulocyte Colony-Stimulating Factor (GCSF) is a pleiotropic cytokine best known for its specific effects on the proliferation, differentiation, and activation of hematopoietic cells of the neutrophilic granulocyte lineage. It is produced mainly by monocytes and macrophages upon activation by endotoxin, TNFα and IFNγ. Other cell types including fibroblasts endothelial cells, astrocytes and bone marrow stromal cells can also secrete GCSF after LPS, IL1 or TNFα activation. In addition, various carcinoma cell lines and myeloblastic leukemia cells can express GCSF constitutively. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues.
Product Source: E. coli
Especificidad
Cross Reactivty
Mouse
Mouse
Aplicación
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
Envase
10 ug
Calidad
Bioactivity assay: Determined by its ability to stimulate the proliferation of mouse M-NFS-60 cells. The expected ED50 is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
Forma física
Product is filtered through a 0.2 micron filter before lyophilization.
Recombinant animal free human G-CSF is manufactured using all non-animal reagents
Almacenamiento y estabilidad
Store at -20°C for up to 6 months from date of receipt.
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 1
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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