8.18737

Chlorotrimethylsilane

for synthesis

• Sinónimos: Chlorotrimethylsilane, Trimethylchlorosilane, Trimethylsilyl chloride, TMCS
• Fórmula lineal: (CH₃)₃SiCl
• Número de CAS: 75-77-4
• Peso molecular: 108.64
• Número MDL: MFCD00000502
• Código UNSPSC: 12352103
• Número índice de la CE: 200-900-5
• NACRES: NA.22

Propiedades

• presión de vapor: 250 hPa ( 20 °C)
• Nivel de calidad: 200
• Análisis: ≥99.0% (GC)
• formulario: liquid
• temp. de autoignición: 420 °C
• potencia: 4868 mg/kg LD₅₀, oral (Rat); 1530 mg/kg LD₅₀, skin (Rabbit)
• lim. expl.: 1.5-46 % (v/v)
• bp: 57 °C/1013 hPa
• mp: -58 °C
• temperatura de transición: flash point -20 °C
• densidad: 0.86 g/cm³ at 20 °C
• temp. de almacenamiento: 2-30°C
• InChI: 1S/C3H9ClSi/c1-5(2,3)4/h1-3H3
• Clave InChI: IJOOHPMOJXWVHK-UHFFFAOYSA-N

Descripción

Aplicación

• Synthesis of bis ferrocene derivatives: Development of new ferrocenyl multi-functional silyl ether compounds using chlorotrimethylsilane, highlighting advances in organosilicon chemistry (R Teimuri-Mofrad et al., 2016).
• Pharmacologically active derivatives: Use of chlorotrimethylsilane as a catalyst in the synthesis of pharmacologically active bis (indolyl) and tris (indolyl) derivatives, demonstrating its efficiency in electrophilic substitution reactions (NG Singh et al., 2014).
• Silicone resin synthesis: Exploration of the hydrolysis-condensation reaction of tetraethoxysilane and chlorotrimethylsilane to create silicone resins, showing the material′s enhanced properties for industrial applications (CFJ Kuo et al., 2014).
• Deoxygenation of unsymmetrical dicarbonyl compounds: Innovative use of chlorotrimethylsilane and sodium iodide for the selective reduction of 1,2-diketones, showcasing a novel method in organic synthesis (LZ Yuan et al., 2016).
• Enhanced activity and durability of catalysts: Investigation into Fe3+ and chlorotrimethylsilane modified NaY catalysts for the acetalization of glycerol to solketal, improving catalytic performance in chemical processes (Y Li et al., 2023).

Nota de análisis

Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.858 - 0.861
Identity (IR): passes test

Información de seguridad

• Pictogramas: GHS02,GHS05,GHS06
• Palabra de señalización: Danger
• Frases de peligro: H225 - H301 + H331 - H312 - H314
• Consejos de prudencia: P210 - P233 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A
• Riesgos supl.: EUH014
• Código de clase de almacenamiento: 3 - Flammable liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): -18.4 °F - closed cup
• Punto de inflamabilidad (°C): -28 °C - closed cup