52619

Hexamethyldisilazane

for GC derivatization, LiChropur^™, ≥99.0% (GC)

• Sinónimos: HMDS
• Fórmula lineal: (CH₃)₃SiNHSi(CH₃)₃
• Número de CAS: 999-97-3
• Peso molecular: 161.39
• Beilstein: 635752
• Número CE: 213-668-5
• Número MDL: MFCD00008259
• Código UNSPSC: 12000000
• ID de la sustancia en PubChem: 329757861
• NACRES: NA.22

Propiedades

• grado: for GC derivatization
• Nivel de calidad: 100
• Análisis: ≥99.0% (GC)
• formulario: liquid
• calidad: LiChropur^™
• idoneidad de la reacción: reagent type: derivatization reagent; reaction type: Silylations
• técnicas: gas chromatography (GC): suitable
• índice de refracción: n20/D 1.407 (lit.); n20/D 1.408
• bp: 125 °C (lit.)
• cadena SMILES: C[Si](C)(C)N[Si](C)(C)C
• InChI: 1S/C6H19NSi2/c1-8(2,3)7-9(4,5)6/h7H,1-6H3
• Clave InChI: FFUAGWLWBBFQJT-UHFFFAOYSA-N

Descripción

Descripción general

Hexamethyldisilazane (HMDS) is a commercially available, silylating agent, which is used as an alternative for the preparation of silyl ethers from hydroxyl compounds.

Aplicación

Learn more in the Product Information

Hexamethyldisilazane is suitable for the derivatization of alcohols, U-aminobutyric acid, pesticidal carbamates and urea, 3,4-Dihydroxyphenylglycol, 4-hydroxycoumarins, hydroxyfatty acids, n-hydroxy-2-fluorenylacetamide, kerb cycle acid, malonaldehyde, monoglycerides, phenylpyruvic acid, shikimic acid, unsaturated fatty acid esters (or methyl esters), and related compounds.

It may be used as a derivatizing reagent for the analysis of bioamines and their acidic metabolites, phenol, hydroquinone and catechol in urine samples, mixtures of free fatty acids and metal soaps in paint samples using gas chromatography/mass spectrometry (GC/MS).

Suitable for the derivatization of alcohols, Υ-aminobutyric acid, pesticidal carbamates and urea, 3,4-Dihydroxyphenylglycol, 4-hydroxycoumarins, hydroxyfatty acids, n-hydroxy-2-fluorenylacetamide, kerb cycle acid, malonaldehyde, monoglycerides, phenylpyruvic acid, shikimic acid, unsaturated fatty acid esters (or methyl esters), and related compounds.

Características y beneficios

• HMDS is inexpensive and has a relatively low boiling point (124-127 °C).        
• It can be used without solvent but its silylating power can be increased by various (mostly acidic) catalysts.        
• The only reaction byproduct, ammonia, can leave the reaction mixture as the reaction goes to completion.

Otras notas

Importante agente sililante

Reagent for 2-hydroxypyrimidine, polytrimethylsilyloxy, trimethylsilyl and trimethylsilyl oximes.

Información legal

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS02,GHS06
• Palabra de señalización: Danger
• Frases de peligro: H225,H302 + H332,H311,H412
• Consejos de prudencia: P210 - P273 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312
• Clasificaciones de peligro: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Flam. Liq. 2
• Código de clase de almacenamiento: 3 - Flammable liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): 52.5 °F - closed cup
• Punto de inflamabilidad (°C): 11.4 °C - closed cup
• Equipo de protección personal: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter