440153

L-α-lysophosphatidylinositol Sodium Salt, Soy

A potent agonist and assumed endogenous ligand of GPR55.

• Sinónimos: L-α-lysophosphatidylinositol Sodium Salt, Soy, L-α-lysophosphatidylinositol LPI, Lyso PI, Soy Lyso PI
• Fórmula empírica (notación de Hill): C₂₅H₄₈NaO₁₂P
• Número de CAS: 796963-91-2
• Peso molecular: 594.61
• Código UNSPSC: 12352200

Propiedades

• Nivel de calidad: 100
• Análisis: >99% (HPLC)
• formulario: powder
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze; desiccated (hygroscopic); protect from light
• color: white
• solubilidad: DMSO: soluble
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C
• cadena SMILES: O[C@H]1[C@H](OP(OC[C@H](O)COC(CCCCCCCCCCCCCCC)=O)([O-][Na+])=O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

Descripción

Descripción general

A potent agonist and assumed endogenous ligand of GPR55, shown to induce rapid phosphorylation of p38 mitogen-activated protein kinase (MAPK) and its downstream activating transcription factor 2 (ATF2) in both GPR55-transfected HEK293 cells, and in IM-9 lymphoblastoid cells naturally expressing GPR55 at 1 µM, while having no effect on vector-transfected cells. In addition, shown to enhance serum induced cell migration in MCF-7 cells over expressing GPR55.

A potent agonist and assumed endogenous ligand of GPR55, shown to induce rapid phosphorylation of p38 mitogen-activated protein kinase (MAPK) and its downstream activating transcription factor 2 (ATF2) in both GPR55-transfected HEK293 cells, and in IM-9 lymphoblastoid cells naturally expressing GPR55 at 1uM, while having no effect on vector-transfected cells. In addition, shown to enhance serum induced cell migration in MCF-7 cells over expressing GPR55.

Envase

Packaged under inert gas

Advertencia

Toxicity: Standard Handling (A)

Otras notas

Oka, S., et al. 2010. J Biochem.147, 671.
Oka, S., et al. 2007.
Biochem. Biophys. Res. Commun.362, 928.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable