850102P

16:0 Lyso PI

1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoinositol (ammonium salt), powder

• Sinónimos: 1-hexadecanoyl-2-hydroxy-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt); PI(16:0/0:0; 110717
• Fórmula empírica (notación de Hill): C₂₅H₅₂NO₁₂P
• Número de CAS: 141553-69-7
• Peso molecular: 589.65
• Código UNSPSC: 51191904
• NACRES: NA.25

Propiedades

• Análisis: >99% (LPI; may contain up to 10% of the 2-LPI isomer, TLC)
• formulario: powder
• envase: pkg of 1 × 100 μg (with stopper and crimp cap (850102P-100ug)); pkg of 1 × 500 μg (with stopper and crimp cap (850102P-500ug))
• fabricante / nombre comercial: Avanti Research^™ - A Croda Brand 850102P
• tipo de lípido: phosphoglycerides
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• cadena SMILES: [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(O)COC(CCCCCCCCCCCCCCC)=O.[NH4+]

Descripción

Descripción general

Lysophosphatidylinositol (LPI) is a bioactive lipid.

Aplicación

16:0 Lyso PI (1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoinositol) has been used as a lipid standard in the optimization of the liquid chromatography–mass spectrometry (LC-MS) method conditions and also has been used as lysophosphatidylinositol (LPI) substrates in lysophosphatidylinositol acyltransferase biochemical assay to assay lyso-phosphatidylinositol acyltransferase (LPIAT) activity of liver microsomes. It may also be used as synthetic LPI to compare its effect with LPI from liver in transferrin (Tf)mediated endocytosis.

Acciones bioquímicas o fisiológicas

Increased circulating levels of L-alpha-lysophosphatidylinositol (LPI) are associated with cancer and LPI is a potent ligand for the G-protein-coupled receptor GPR55.

Lysophosphatidylinositol (LPI) has the ability to modulate cancer cell migration. It can control the functions of endothelium. LPI can serve as an autocrine regulator of cell growth, hence its known to participate in cancer progression. It can stimulate signaling cascades, that are essential for survival, migration and proliferation of cells.

Envase

2 mL Amber Serum Vial with Stopper and Crimp Cap (850102P-100ug)

2 mL Amber Serum Vial with Stopper and Crimp Cap (850102P-500ug)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): No data available
• Punto de inflamabilidad (°C): No data available