M-132

N-Metil-N-(trimetilsilil)trifluoroacetamida

ampule of 10 × 1.2 mL, analytical standard, Cerilliant^®

• Sinónimos: N-trimetilsilil-N- metil trifluoroacetamida, MSTFA
• Fórmula lineal: CF₃CON(CH₃)Si(CH₃)₃
• Número de CAS: 24589-78-4
• Peso molecular: 199.25
• Beilstein: 1941550
• Número CE: 246-331-6
• Número MDL: MFCD00000411
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329817869
• NACRES: NA.24

Propiedades

• grado: analytical standard
• Nivel de calidad: 100
• densidad de vapor: >1 (vs air)
• presión de vapor: 8.8 mmHg ( 27 °C)
• idoneidad de la reacción: reagent type: derivatization reagent; reaction type: Acylations
• envase: ampule of 10 × 1.2 mL
• fabricante / nombre comercial: Cerilliant^®
• técnicas: gas chromatography (GC): suitable
• índice de refracción: n20/D 1.38 (lit.)
• bp: 130-132 °C (lit.)
• densidad: 1.075 g/mL at 25 °C (lit.)
• aplicaciones: forensics and toxicology
• Formato: neat
• temp. de almacenamiento: −20°C
• cadena SMILES: CN(C(=O)C(F)(F)F)[Si](C)(C)C
• InChI: 1S/C6H12F3NOSi/c1-10(12(2,3)4)5(11)6(7,8)9/h1-4H3
• Clave InChI: MSPCIZMDDUQPGJ-UHFFFAOYSA-N

Descripción

Descripción general

MSTFA (N-Methyl-N-trimethylsilylfluoroacetamide) is an important trimethylsilyl reagent, and a commonly applied reagent since it is highly reactive towards a broad range of compound classes. GC-MS optimization studies reveal the use of this reagent either alone or in combination with 1% of trimethylchlorosilane as a catalyst for silylation of complex mixtures. It has similar reactivity as BSA and BSTFA.

Aplicación

MSTFA reagent may be used as a derivatizing agent in the following:

• Analysis of estrogen steroids such as estrone (E1), 17α-ethinylestradiol (EE2), and trenbolone acetate metabolites, melengestrol in environmental matrices using gas chromatography coupled to mass spectrometry (GC-MS).
• Quantification of ibuprofen, naproxen, ketoprofen, and diclofenac in wastewater samples using gas chromatography coupled to mass spectrometry (GC-MS).

Características y beneficios

• Very volatile of TMS-acetamides.
• More volatile than BSA or BSTFA but with similar silylation strength.
• Useful in the analysis of volatile trace materials.
• Used in the preparation of volatile and thermally stable derivatives for GC and MS analysis.

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS02,GHS07
• Palabra de señalización: Warning
• Frases de peligro: H226,H315,H319,H335
• Consejos de prudencia: P210 - P302 + P352 - P305 + P351 + P338
• Clasificaciones de peligro: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• Órganos de actuación: Respiratory system
• Código de clase de almacenamiento: 3 - Flammable liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): 78.8 °F - closed cup
• Punto de inflamabilidad (°C): 26 °C - closed cup