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850371C

Avanti

22:0 PC

1,2-dibehenoyl-sn-glycero-3-phosphocholine, chloroform

Sinónimos:

1,2-didocosanoyl-sn-glycero-3-phosphocholine; PC(22:0/22:0)

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About This Item

Fórmula empírica (notación de Hill):
C52H104NO8P
Número de CAS:
37070-48-7
Peso molecular:
902.36
Código UNSPSC:
51191904
NACRES:
NA.25

Análisis

>99% (TLC)

formulario

liquid

envase

pkg of 1 × 2.5 mL (850371C-25mg)
pkg of 1 × 20 mL (850371C-500mg)

fabricante / nombre comercial

Avanti Research™ - A Croda Brand 850371C

concentración

10 mg/mL (850371C-25mg)
25 mg/mL (850371C-500mg)

tipo de lípido

cardiolipins
phospholipids

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

InChI

1S/C52H104NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-42-44-51(54)58-48-50(49-60-62(56,57)59-47-46-53(3,4)5)61-52(55)45-43-41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h50H,6-49H2,1-5H3

Clave InChI

HRTBOPUWPUXROO-UHFFFAOYSA-N

Descripción general

Phosphatidylcholines are phospholipids, that are abundantly present in the membrane. They have fatty acids in the sn-1 and sn-2 positions, that are covalently attached to a glycerol with the help of ester bonds.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Aplicación

22:0 PC may be used:
  • to study its effects on non-amyloidogenic processing of amyloid precursor protein (APP)/α-secretase activity
  • to prepare a lipid monolayer to study whether ligand is specifically targeted to domains containing Cu(II)-iminodiacetate lipid (Cu-PSIDA)
  • as a lipid standard for the quantification of lipid species from lipid droplets by hydrophilic interaction liquid chromatography-high performance liquid chromatography (HILIC-HPLC)

Acciones bioquímicas o fisiológicas

The physical properties of membranes can be modulated with the help of fatty acyl configuration of phosphatidylcholines. They act as a vital source for eicosanoids.

Envase

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850371C-500mg)
5 mL Clear Glass Sealed Ampule (850371C-25mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

también adquirido normalmente con este producto

Referencia del producto
Descripción
Precios

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Órganos de actuación

Liver,Kidney, Respiratory system

Código de clase de almacenamiento

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

does not flash

Punto de inflamabilidad (°C)

does not flash

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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International journal of molecular sciences, 14(3), 5879-5898 (2013-03-15)
Alzheimer's disease (AD) is characterized by extracellular accumulation of amyloid-β peptide (Aβ), generated by proteolytic processing of the amyloid precursor protein (APP) by β- and γ-secretase. Aβ generation is inhibited when the initial ectodomain shedding is caused by α-secretase, cleaving

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