810601P
Avanti
16:0-5 Doxyl PC
Avanti Polar Lipids 810601P, powder
Sinónimos:
1-palmitoyl-2-stearoyl-(5-doxyl)-sn-glycero-3-phosphocholine
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About This Item
Fórmula empírica (notación de Hill):
C46H90N2O10P
Número de CAS:
Peso molecular:
862.19
Código UNSPSC:
41141825
NACRES:
NA.25
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Análisis
>99% (TLC)
formulario
powder
envase
pkg of 1 × 1 mg (810601P-1mg)
fabricante / nombre comercial
Avanti Polar Lipids 810601P
tipo de lípido
ESR probes
phospholipids
Condiciones de envío
dry ice
temp. de almacenamiento
−20°C
Categorías relacionadas
Descripción general
Avanti′s nitroxide spin product listing is a group of compounds designed to act as membrane probes. A variety of positions down the hydrophobic chain are labeled with the nitroxide functional groups to allow probing the membrane at various depths. These compounds have been synthesized from 1-palmitoyl-2-hydroxy-sn-glycerol-3-phosphocholine with the product being purified by column chromatography. Various n-doxyl phosphocholines have been recently used as biophysical tools to elucidate membrane trafficking with phosphatidylinositol transfer proteins and as fluorescent quenchers in lipid bilayer structural studies.
Phosphatidylcholine (PC), a strong bilayer-forming lipid is the most common phospholipid in mammalian membranes. The excretory and secretory products of helminths has a small hapten-like portion called phosphorylcholine (PC). The 5th carbon of the sn-2 stearic acid chain of 1-palmitoyl-2-stearoyl-(5-doxyl)-sn-glycero-3-phosphocholine analog has a Doxyl PC, a spin probe attached to it covalently.
Aplicación
16:0-5 Doxyl PC may be used:
- as a component in virus-like large unilamellar vesicles (VL LUVs) to quench 4-chloro-7-nitrobenz-2-oxa-1,3-diazole (NBD) fluorescence emission
- in the preparation of multi-lamellar vesicles (MLVs) as a site-specific quencher to perform fluorescence quenching studies
- in the preparation of spin-labelled multi-lamellar vesicles (MLVs)
Acciones bioquímicas o fisiológicas
Phosphatidylcholine (PC) lowers the levels of cholesterol and triglycerides.
Envase
5 mL Clear Glass Sealed Ampule (810601P-1mg)
Nota de preparación
Product use: To prevent aggregation, prepare water-based solutions of 2 mM stock solutions of n-DOXYL PCs and store in plastic. Dilute stock solutions to 0.03- 0.1 mM solutions for EPR studies. For liposome preparations in fluorescent quenching measurements, dissolve the doxyl lipid in 150 μl absolute ethanol for a concentration of 40.3 mM , Additional supplemental information.
Información legal
Avanti Research is a trademark of Avanti Polar Lipids, LLC
también adquirido normalmente con este producto
Referencia del producto
Descripción
Precios
Código de clase de almacenamiento
11 - Combustible Solids
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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