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Merck

W318101

Sigma-Aldrich

2-Methoxycinnamaldehyde

natural, 98%, FG

Sinónimos:

o-Methoxycinnamaldehyde

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About This Item

Fórmula lineal:
CH3OC6H4CH=CHCHO
Número de CAS:
Peso molecular:
162.19
Número de FEMA:
3181
Número CE:
nº del Consejo Europeo:
571
Número MDL:
Código UNSPSC:
12164502
ID de la sustancia en PubChem:
Número Flavis:
5.048
NACRES:
NA.21

grado

FG
Fragrance grade
Halal
Kosher
natural

Agency

follows IFRA guidelines

cumplimiento norm.

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 172.515

Análisis

98%

bp

160-161 °C/12 mmHg (lit.)

mp

44.0-49.0 °C (lit.)

aplicaciones

flavors and fragrances

Documentación

see Safety & Documentation for available documents

alérgeno alimentario

no known allergens

alérgeno de la fragancia

no known allergens

Organoléptico

cinnamon; woody; spicy; sweet

cadena SMILES

[H]C(=O)C=Cc1ccccc1OC

InChI

1S/C10H10O2/c1-12-10-7-3-2-5-9(10)6-4-8-11/h2-8H,1H3/b6-4+

Clave InChI

KKVZAVRSVHUSPL-GQCTYLIASA-N

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Aplicación


  • Network pharmacology combined with molecular docking and experimental validation to explore the potential mechanism of Cinnamomi ramulus against ankylosing spondylitis.: This study investigates the anti-inflammatory potential of 2-Methoxycinnamaldehyde in Cinnamomi ramulus. Its application extends to novel therapeutic approaches for treating ankylosing spondylitis, demonstrating significant implications for medicinal chemistry and pharmacology (Wei et al., 2023).

  • Ramulus Cinnamomi essential oil exerts an anti-inflammatory effect on RAW264.7 cells through N-acylethanolamine acid amidase inhibition.: The study elaborates on the anti-inflammatory activities of 2-Methoxycinnamaldehyde, offering a biochemical pathway that could be exploited in anti-inflammatory drug design (Jia et al., 2023).
  • Metabolomics-Driven Exploration of the Antibacterial Activity and Mechanism of 2-Methoxycinnamaldehyde.: This article offers insights into the antibacterial properties of 2-Methoxycinnamaldehyde, using metabolomics to explore its mechanism of action, significant for developments in antimicrobial treatments (Qian et al., 2022).


Pictogramas

Exclamation mark

Palabra de señalización

Warning

Frases de peligro

Clasificaciones de peligro

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órganos de actuación

Respiratory system

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

235.4 °F

Punto de inflamabilidad (°C)

113 °C


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Jian-you Guo et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 31(13), 1087-1090 (2006-10-20)
To observe the effect of 2-methoxycinnamaldehyde (isolated from fraction A of Guizhi Tang) on activity of COX and PGE2 release in rat cerebral microvascular endothelial cells (rCMEC) stimulated by IL-1. rCMEC were cultured, and identified by immunohistochemistry for von Willebrand
R Giordani et al.
Phytotherapy research : PTR, 20(1), 58-61 (2006-01-07)
The antifungal activity of the essential oil from Cinnamomum cassia, alone or combined with amphotericin B, a drug widely used for most indications despite side-effects was investigated. The composition of the oil was analysed by GC/MS and characterized by its
O B Samuelsen et al.
Xenobiotica; the fate of foreign compounds in biological systems, 16(9), 845-852 (1986-09-01)
The metabolism of o-methoxycinnamaldehyde (1.3 mmol/kg, intragastrically) was studied in rats. Identification of the urinary metabolites by g.l.c.-mass spectrometry and quantification by h.p.l.c. showed that the major metabolic pathway (approx. two-thirds of the dose) was oxidation to the corresponding cinnamic
R Montes-Belmont et al.
Journal of food protection, 61(5), 616-619 (1998-08-26)
The effects of 11 plant essential oils for maize kernel protection against Aspergillus flavus were studied. Tests were conducted to determine optimal levels of dosages for maize protection, effects of combinations of essential oils, and residual effects and toxicity of
Guang-Ping Lv et al.
Journal of separation science, 33(15), 2341-2348 (2010-06-24)
A pressurized liquid extraction and GC-MS method was developed for simultaneous quantitative determination of the seven components, including cinnamaldehyde, copaene, cinnamic acid, coumarin, 2-methoxycinnamaldehyde, 2-methoxycinnamic acid and safrole in Cinnamomum cassia. The results showed that methanol and ethanol was not

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