Saltar al contenido
Merck
Todas las fotos(1)

Documentos clave

Ver Toda la documentación

914088

Sigma-Aldrich

N6-((2-Azidoethoxy)carbonyl)-L-lysine hydrochloride

≥95%

Sinónimos:

(S)-2-amino-6-((2-azidoethoxy)carbonylamino)hexanoic acid hydrochloride, Clickable amino acid for bioconjugation, H-L-Lys(EO-N3)-OH HCl, Lysine-azide, UAA crosslinker

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula empírica (notación de Hill):
C9H17N5O4 · xHCl
Número de CAS:
1994331-17-7
Peso molecular:
259.26 (free base basis)
Número MDL:
MFCD32066830
Código UNSPSC:
12352209

Nivel de calidad

100

Ensayo

≥95%

Formulario

powder

temp. de almacenamiento

−20°C

cadena SMILES

[N+](=[N-])=NCCOC(=O)NCCCC[C@H](N)C(=O)O.C

InChI

1S/C9H17N5O4.CH4/c10-7(8(15)16)3-1-2-4-12-9(17)18-6-5-13-14-11;/h7H,1-6,10H2,(H,12,17)(H,15,16);1H4/t7-;/m0./s1

Clave InChI

LQERWAMRZNEGIE-FJXQXJEOSA-N

Aplicación

N6-((2-Azidoethoxy)carbonyl)-L-lysine hydrochloride is a clickable amino acid derivative for site-specific incorporation into recombinant proteins or synthesis of chemical probes and tools for biological applications. This non-canonical lysine possesses an azide for bioorthogonal reaction with alkynes.

Otras notas

Construction of bacterial cells with an active transport system for unnatural amino acids

Semisynthesis of an Active Enzyme by Quantitative Click Ligation

A Robust and Quantitative Reporter System To Evaluate Noncanonical Amino Acid Incorporation in Yeast

An orthogonalized platform for genetic code expansion in both bacteria and eukaryotes

Producto relacionado

Referencia del producto
Descripción
Precios

F4438

Fmoc-Lys(Me,Boc)-OH, ≥97%

900892

L-Azidohomoalanine hydrochloride

907251

H-L-Photo-lysine HCl, ≥98%

907383

Fmoc-L-Photo-Lysine, ≥95%

909564

4-Azido-L-phenylalanine, ≥98%

909823

3-Azido-D-alanine hydrochloride, ≥95%

914339

Fmoc-L-Lys(Nvoc)-OH, ≥98%

914827

N6-((Prop-2-yn-1-yloxy)carbonyl)-L-lysine hydrochloride, ≥98%

Pictogramas

Flame
GHS02

Palabra de señalización

Danger

Frases de peligro

H242

Clasificaciones de peligro

Self-react. C

Código de clase de almacenamiento

5.2 - Organic peroxides and self-reacting hazardous materials

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documentos section.

Si necesita más asistencia, póngase en contacto con Atención al cliente

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Siqi Zheng et al.
Angewandte Chemie (International ed. in English), 53(25), 6449-6453 (2014-05-16)
Coupling the genetic code expansion technique with bioorthogonal reactions enables precise control over the conjugation site as well as the choice of fluorescent probes during protein labeling. However, the advantages of this strategy over bulky and rigid fluorescent proteins (FPs)
Chuanling Zhang et al.
Biomaterials, 80, 134-145 (2015-12-29)
Virus-based nanoparticles have shown promise as vehicles for delivering therapeutic genes. However, the rational design of viral vectors that enable selective tropism towards particular types of cells and tissues remains challenging. Here, we explored structural-functional relationships of the adeno-associated virus
Sanggil Kim et al.
Bioorganic & medicinal chemistry, 24(22), 5816-5822 (2016-10-26)
Proteins often function as complex structures in conjunction with other proteins. Because these complex structures are essential for sophisticated functions, developing protein-protein conjugates has gained research interest. In this study, site-specific protein-protein conjugation was performed by genetically incorporating an azide-containing
Michael P VanBrunt et al.
Bioconjugate chemistry, 26(11), 2249-2260 (2015-09-04)
Antibody-drug conjugates (ADC) have emerged as potent antitumor drugs that provide increased efficacy, specificity, and tolerability over chemotherapy for the treatment of cancer. ADCs generated by targeting cysteines and lysines on the antibody have shown efficacy, but these products are
Yiming Wu et al.
Bioconjugate chemistry, 27(10), 2460-2468 (2016-10-21)
Radioimmunotherapy (RIT) delivers radioisotopes to antigen-expressing cells via monoantibodies for the imaging of lesions or medical therapy. The chelates are typically conjugated to the antibody through cysteine or lysine residues, resulting in heterogeneous chelate-to-antibody ratios and various conjugation sites. To
Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico