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Sigma-Aldrich

Resomer® RG 504 H, Poly(D,L-lactide-co-glycolide)

acid terminated, lactide:glycolide 50:50, Mw 38,000-54,000

Sinónimos:

PLGA

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About This Item

Fórmula lineal:
[C3H4O2]x[C2H2O2]y
Número de CAS:
26780-50-7
Código UNSPSC:
12162002
NACRES:
NA.23

formulario

amorphous

cociente alimentación

lactide:glycolide 50:50

mol peso

Mw 38,000-54,000

marco temporal de la degradación

<3 months

viscosidad

0.45-0.60 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

temperatura de transición

Tg 46-50 °C

temp. de almacenamiento

2-8°C

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

Clave InChI

LCSKNASZPVZHEG-UHFFFAOYSA-N

Aplicación

Resomer® RG 504 H, Poly(D, L-Lactide-co-Glycolide) can be used to fabricate a biodegradable hemostyptic device for safe and locally controlled release of thrombin which promotes local blood clot formation.

It can be used to preparepolymer nanospheres for encapsulating CuO, to form stimuli-responsivemultifunctional nanocarriers.

Información legal

Product of Evonik
RESOMER is a registered trademark of Evonik Rohm GmbH

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Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Hossein Kamali et al.
Materials science & engineering. C, Materials for biological applications, 96, 561-575 (2019-01-05)
An in situ forming gel (ISFG) of buprenorphine (BP) was prepared using PLGA-PEG-PLGA (triblock) and N‑methyl‑2‑pyrrolidone as solvent for decreasing the initial burst release. Supercritical CO2 method was used for ring opening polymerization of triblock. The optimum formulation of ISFG
Niranjan G Kotla et al.
Nanomaterials (Basel, Switzerland), 9(9) (2019-09-05)
There is a pressing clinical need for advanced colon-specific local drug delivery systems that can provide major advantages in treating diseases associated with the colon, such as inflammatory bowel disease (IBD) and colon cancer. A precise colon targeted drug delivery
Rongcai Liang et al.
International journal of pharmaceutics, 454(1), 344-353 (2013-07-23)
Peptide or protein degradation often occurs when water flows into the dosage form. The aim of this study was to investigate the effect of water on exenatide acylation in poly(lactide-co-glycolide) (PLGA) microspheres. Exenatide-loaded PLGA microspheres were incubated at different relative
Shu-Chun Chuang et al.
Parasites & vectors, 6, 34-34 (2013-02-13)
Current development efforts of subunit vaccines against Toxoplasma gondii, the etiological agent of toxoplasmosis, have been focused mainly on tachyzoite surface antigen 1 (SAG1). Since microparticles made from poly (lactide-co-glycolide) (PLG) polymers have been developed as safe, potent adjuvants or
Vanna Sanna et al.
International journal of nanomedicine, 7, 5501-5516 (2012-10-25)
Resveratrol, like other natural polyphenols, is an extremely photosensitive compound with low chemical stability, which limits the therapeutic application of its beneficial effects. The development of innovative formulation strategies, able to overcome physicochemical and pharmacokinetic limitations of this compound, may
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