1332000

Hydroxyharnstoff

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): Hydroxycarbamid
• Lineare Formel: NH₂CONHOH
• CAS-Nummer: 127-07-1
• Molekulargewicht: 76.05
• Beilstein: 1741548
• MDL-Nummer: MFCD00007943
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329750138
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: hydroxyurea
• Hersteller/Markenname: USP
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: NC(=O)NO
• InChI: 1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)
• InChIKey: VSNHCAURESNICA-UHFFFAOYSA-N
• Angaben zum Gen: human ... RRM1(6240) , RRM2(6241) , RRM2B(50484)

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem./physiol. Wirkung

Anti-neoplastisch. Inaktiviert die Ribonukleosid-Reduktase durch Bildung eines freien Nitroxid-Radikals, das ein freies Tyrosyl-Radikal im aktiven Zentrum des Enzyms bindet. Dadurch wird die Synthese von Desoxynukleotiden blockiert, was die DNA-Synthese hemmt und die Synchronisation oder den Zelltod in der S-Phase induziert.

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H340,H361
• P-Sätze: P201 - P280 - P308 + P313
• Gefahreneinstufungen: Muta. 1B - Repr. 2
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable