1302214

Guggulsteron Z

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): (Z)-Guggulsteron, (17Z)-Pregna-4,17(20)-dien-3,16-dion, 4,17(20)-trans-Pregnadien-3,16-dion
• Empirische Formel (Hill-System): C₂₁H₂₈O₂
• CAS-Nummer: 39025-23-5
• Molekulargewicht: 312.45
• MDL-Nummer: MFCD01310757
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329749979
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: guggul
• Hersteller/Markenname: USP
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: −20°C
• SMILES String: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)\C(=C\C)C(=O)C[C@@]24[H]
• InChI: 1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4+/t15-,17+,18+,20+,21-/m1/s1
• InChIKey: WDXRGPWQVHZTQJ-OSJVMJFVSA-N

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Guggulsterone Z USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Guggul
• Guggul Tablets
• Native Guggul Extract
• Purified Guggul Extract

Biochem./physiol. Wirkung

(Z)-Guggulsterone is a natural product that lowers cholesterol due to its function as an antagonist ligand for the bile acid receptor. (Z)-Guggulsterone is a nuclear hormone receptor that regulates the transcription of several genes involved in cholesterol metabolism and plays a role in cholesterol level regulation. (Z)-Guggulsterone is also a selective farnesoid X receptor (FXR) modulator.

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H335
• P-Sätze: P261 - P271 - P304 + P340 + P312 - P403 + P233 - P405 - P501
• Gefahreneinstufungen: STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable