G5168

(Z)-Guggulsteron

≥89% (HPLC), powder

• Synonym(e): (17Z)-Pregna-4,17(20)-dien-3,16-dion, 4,17(20)-trans-Pregnadien-3,16-dion
• Empirische Formel (Hill-System): C₂₁H₂₈O₂
• CAS-Nummer: 39025-23-5
• Molekulargewicht: 312.45
• MDL-Nummer: MFCD01310757
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24278392
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥89% (HPLC)
• Form: powder
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Verunreinigungen: ≤5.4% E-form
• Farbe: light yellow
• Löslichkeit: DMSO: 5 mg/mL
• Anwendung(en): forensics and toxicology; veterinary
• Lagertemp.: 2-8°C
• SMILES String: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)\C(=C\C)C(=O)C[C@@]24[H]
• InChI: 1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4+/t15-,17+,18+,20+,21-/m1/s1
• InChIKey: WDXRGPWQVHZTQJ-OSJVMJFVSA-N

Beschreibung

Biochem./physiol. Wirkung

(Z)-Guggulsterone is a natural product that lowers cholesterol due to its function as an antagonist ligand for the bile acid receptor. (Z)-Guggulsterone is a nuclear hormone receptor that regulates the transcription of several genes involved in cholesterol metabolism and plays a role in cholesterol level regulation. (Z)-Guggulsterone is also a selective farnesoid X receptor (FXR) modulator.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H335
• P-Sätze: P261 - P271 - P304 + P340 + P312 - P403 + P233 - P405 - P501
• Gefahreneinstufungen: STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves