SML3334

Ceefourin 1

≥95% (HPLC)

• Synonym(e): 5-[(2-Benzothiazolylthio)methyl]-2,4-dihydro-4-methyl-3H-1,2,4-triazole-3-thione, Ceefourin-1
• Empirische Formel (Hill-System): C₁₁H₁₀N₄S₃
• CAS-Nummer: 315702-40-0
• Molekulargewicht: 294.42
• MDL-Nummer: MFCD02329957
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥95% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: -10 to -25°C
• SMILES String: CN1C(CSC2=NC3=C(C=CC=C3)S2)=NNC1=S

Beschreibung

Biochem./physiol. Wirkung

Ceefourin 1 is a potent and highly selective MRP4 (Multidrug resistance protein 4) inhibitor that exhibits low cellular toxicity and high microsomal and acid stability. Ceefourin 1 inhibits PDAC (pancreatic ductal adenocarcinoma) cell proliferation through MRP4-dependent cAMP extrusion thereby activation of the cAMP/Epac/Rap1 signaling pathway.

Potent and highly selective MRP4 (Multidrug resistance protein 4) inhibitor

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable