SML2361

Kinesore

>97% (HPLC)

• Synonym(e): 3,5-Dibromo-4-hydroxy-benzoic acid 2-[[2,5-dimethyl-1-(3-nitrophenyl)-1H-pyrrol-3-yl]methylene]hydrazide, 3,5-Dibromo-N′-{[2,5-dimethyl-1-(3-nitrophenyl)-1H-pyrrol-3-yl]methylene}-4-hydroxybenzohydrazide
• Empirische Formel (Hill-System): C₂₀H₁₆Br₂N₄O₄
• CAS-Nummer: 363571-83-9
• Molekulargewicht: 536.17
• MDL-Nummer: MFCD02636553
• UNSPSC-Code: 31401503
• NACRES: NA.77

Eigenschaften

• Assay: >97% (HPLC)
• Form: powder
• Farbe: white to brown
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: 2-8°C

Beschreibung

Biochem./physiol. Wirkung

Kinesore is a cell penetrant and potent activator of kinesin-1 that induces kinesin light chain tetratricopeptide repeat domain-dependent kinesin-1 activation in the absence of organelle cargo-adaptor engagement. It inhibits kinesin-1 interaction with peptide fragment of organelle-specific cargo adaptors. Kinesore induces kinesin light chain conformational switch that causes remodeling of the microtubule network in cells.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable