SML2088

Procainamid -hydrochlorid

≥98% (HPLC), powder, sodium channel blocker

• Synonym(e): Procainamid -hydrochlorid, 4-Amino-benzoesäure-2-diethylaminoethylamid, 4-Amino-N-(2-diethylaminoethyl)-benzamid -hydrochlorid, 4-Amino-benzoesäure-2-diethylaminoethylamid -hydrochlorid
• Lineare Formel: H₂NC₆H₄CONHCH₂CH₂N(C₂H₅)₂·HCl
• CAS-Nummer: 614-39-1
• Molekulargewicht: 271.79
• Beilstein: 3729517
• EG-Nummer: 210-381-7
• MDL-Nummer: MFCD00012998
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• product name: Procainamid -hydrochlorid, ≥98% (HPLC)
• Assay: ≥98% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: white to beige
• mp (Schmelzpunkt): 167-169 °C (lit.)
• Löslichkeit: H₂O: 2 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: Cl.CCN(CC)CCNC(=O)c1ccc(N)cc1
• InChI: 1S/C13H21N3O.ClH/c1-3-16(4-2)10-9-15-13(17)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3,(H,15,17);1H
• InChIKey: ABTXGJFUQRCPNH-UHFFFAOYSA-N
• Angaben zum Gen: human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

Beschreibung

Anwendung

Procainamide hydrochloride (PAH) is suitable to investigate its binding behavior with human serum albumin and bovine serum albumin by fluorescence quenching study to understand the pharmacokinetic and pharmacodynamic mechanisms of PAH.

Biochem./physiol. Wirkung

Procainamide hydrochloride is a sodium channel blocker and Class IA anti-arrhythmic. It has also been shown to Inhibit DNA methyltransferase and modulate epigenetic regulation of gene expression.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H315,H319,H335
• P-Sätze: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3