SML0465

Symadex

≥98% (HPLC)

• Synonym(e): 5-[[2-(Diethylamino)ethyl]amino]-8-hydroxy-6H-Imidazo[4,5,1-de]acridin-6-one, C-1311, C1311
• Empirische Formel (Hill-System): C₂₀H₂₂N₄O₂
• CAS-Nummer: 138154-39-9
• Molekulargewicht: 350.41
• MDL-Nummer: MFCD00947296
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329824743
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 10 mg/mL (clear solution; warmed)
• Lagertemp.: 2-8°C
• SMILES String: CCN(CC)CCNc1ccc2ncn3-c4ccc(O)cc4C(=O)c1c23
• InChI: 1S/C20H22N4O2/c1-3-23(4-2)10-9-21-15-6-7-16-19-18(15)20(26)14-11-13(25)5-8-17(14)24(19)12-22-16/h5-8,11-12,21,25H,3-4,9-10H2,1-2H3
• InChIKey: CUNDRHORZHFPLY-UHFFFAOYSA-N
• Angaben zum Gen: human ... FLT3(2322) , TOP2A(7153) , TOP2B(7155)

Beschreibung

Biochem./physiol. Wirkung

Symadex is a FLT3 and topoisomerase-II inhibitor; ABCG2 substrate; cell cycle modulator.

Symadex is an FMS-like tyrosine kinase 3 (FLT3) and topoisomerase-II inhibitor; ABCG2 substrate; cell cycle modulator.

Leistungsmerkmale und Vorteile

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the PDGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• P-Sätze: P264 - P270 - P301 + P312 - P501
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable