SML0285

Pleuromutilin

≥95%

• Synonym(e): Drosophilin B, Mutilin 14-glycolate, NSC 121145
• Empirische Formel (Hill-System): C₂₂H₃₄O₅
• CAS-Nummer: 125-65-5
• Molekulargewicht: 378.50
• EG-Nummer: 204-747-5
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825293
• NACRES: NA.77

Eigenschaften

• Assay: ≥95%
• Form: powder
• Optische Aktivität: [α]/D +30 to +40° (c=1; CH2Cl2)
• Farbe: white to beige
• Löslichkeit: DMSO: >10 mg/mL (warmed)
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• SMILES String: C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@]1(C)[C@@H](C[C@@](C)(C=C)[C@@H](O)[C@@H]3C)OC(=O)CO
• InChI: 1S/C22H34O5/c1-6-20(4)11-16(27-17(25)12-23)21(5)13(2)7-9-22(14(3)19(20)26)10-8-15(24)18(21)22/h6,13-14,16,18-19,23,26H,1,7-12H2,2-5H3/t13-,14+,16-,18+,19+,20-,21+,22+/m1/s1
• InChIKey: ZRZNJUXESFHSIO-BKUNHTPHSA-N

Beschreibung

Biochem./physiol. Wirkung

Pleuromutilin is a diterpene that acts against gram positive bacteria and mycoplasm. It is present in Pleurotus mutilus and Pleurotus passecherianus. Pleuromutilin exhibits its antibacterial action by interfering with the prokaryotic 70S ribosomal subunit and inactivates initiation complex. Pleuromutilin is useful in treating mycoplasma infections in animals.

Pleuromutilin is an antibiotic natural product that inhibits bacterial protein synthesis by binding to bacterial ribosomes in the peptidyl transferase center and inhibiting peptide bond formation.

Sicherheitshinweise

• Piktogramme: GHS07,GHS09
• Signalwort: Warning
• H-Sätze: H302,H410
• P-Sätze: P264 - P270 - P273 - P301 + P312 - P391 - P501
• Gefahreneinstufungen: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable