SBR00057

Retapamulin

≥98% (HPLC)

• Empirische Formel (Hill-System): C₃₀H₄₇NO₄S
• CAS-Nummer: 224452-66-8
• Molekulargewicht: 517.76
• MDL-Nummer: MFCD11045316
• UNSPSC-Code: 51284706
• NACRES: NA.76

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Wirkungsspektrum von Antibiotika: Gram-positive bacteria
• Wirkungsweise: protein synthesis | interferes
• Lagertemp.: −20°C
• SMILES String: S(C4C[C@@H]5N([C@@H](CC5)C4)C)CC(=O)O[C@H]1[C@]2([C@H]3[C@@]([C@H]([C@@H]([C@](C1)(C)C=C)O)C)(CC[C@H]2C)CCC3=O)C
• InChI: 1S/C30H47NO4S/c1-7-28(4)16-24(35-25(33)17-36-22-14-20-8-9-21(15-22)31(20)6)29(5)18(2)10-12-30(19(3)27(28)34)13-11-23(32)26(29)30/h7,18-22,24,26-27,34H,1,8-17H2,2-6H3/t18-,19+,20-,21+,22?,24-,26+,27+,28-,29+,30+/m1/s1
• InChIKey: STZYTFJPGGDRJD-FJJJPKKESA-N

Beschreibung

Allgemeine Beschreibung

Retapamulin (RET) is a semi-synthetic antibiotic ointment, and pleuromutilin derivative compound. The primary structural difference between pleuromutilin and retapamulin is in the C-14 side chain.

Biochem./physiol. Wirkung

Retapamulin is a potent antibacterial agent against Gram-positive bacteria, especially against Staphylococcus aureus and S. pyogenes. It displays synergistic effects against Enterococcus faecalis in combination with streptogramin (MLS). RET initiates ribosomal arrests at the start codon and enables genes to use alternative translational sites in E. coli.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable