SAB4502360

Anti-PKC δ antibody produced in rabbit

affinity isolated antibody

• Synonym(e): KPCD, PKC-δ, PRKCD, kinase PKC-δ, nPKC-δ
• MDL-Nummer: MFCD00162772
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 77 kDa
• Speziesreaktivität: human, mouse, rat
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:1000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: Q05655
• UniProt-Hinterlegungsnummer: Q05655
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... PRKCD(5580)

Beschreibung

Allgemeine Beschreibung

Anti-PKC δ antibody detects endogenous levels of total PKC δ protein.

The PKC δ (protein kinase C δ) gene is mapped to human chromosome 3p21.1. It is predominantly expressed in the heart.

Immunogen

The antiserum was produced against synthesized peptide derived from human PKC delta.

Immunogen Range: 471-520

Biochem./physiol. Wirkung

The PKC (protein kinase C) protein is known to mediate different cellular processes such as transcription regulation, cell signaling, cell proliferation, immune responses and apoptosis. PKC is also associated with learning ability. Abnormal cell signaling induced by PKC is often observed in cancer. PKC δ (protein kinase C δ) regulates neutrophil migration during sepsis. PKC δ has anticancer effect by reducing the cell proliferation rate and also stimulating apoptosis by arresting cell cycle. PKC δ induces neuron proliferation and survival, thereby it is associated with memory.

Leistungsmerkmale und Vorteile

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Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable