AV50526

Anti-APC2 antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-APCL, Anti-Adenomatosis polyposis coli 2
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: 244 kDa
• Speziesreaktivität: mouse, bovine, rat, dog, human, guinea pig
• Konzentration: 0.5 mg - 1 mg/mL
• Methode(n): immunohistochemistry: suitable; western blot: suitable
• NCBI-Hinterlegungsnummer: NP_005874
• UniProt-Hinterlegungsnummer: Q9UJX6
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... APC2(10297)

Beschreibung

Immunogen

Synthetic peptide directed towards the middle region of human APC2

Anwendung

Anti-APC2 antibody produced in rabbit is suitable for western blotting at a concentration of 0.5μg/ml and for immunohistochemistry of paraffin-embedded tissue sections at a concentration of 4-8μg/ml.

Biochem./physiol. Wirkung

Adenomatosis polyposis coli 2 (APC2) is a tumor suppressor and a negative regulator of Wnt signaling pathway. The C-terminal of APC interacts with microtubules and is important for cytoskeletal regulation. The expression of APC2 and Axin protein is required to maintain the fidelity of mitosis as they regulate cytoskeleton and facilitate centrosome separation.

Sequenz

Synthetic peptide located within the following region: LAVARIDQLVEDISALHTSSDDSFSLSSGDPGQEAPREGRAQSCSPCRGP

Physikalische Form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable